ArticleHuman brain mapping2015
Assessing hippocampal development and language in early childhood: Evidence from a new application of the Automatic Segmentation Adapter Tool.
Article in Human brain mapping, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic literature review of sex differences in childhood language and brain development.Neuropsychologia · 2018Pooled it
- Age-related volumetric differences of hippocampal subfields in the developing brain: a retrospective MRI study.Brain structure & function · 2026Article
- Neuroanatomical basis of language ability in an autism subgroup with moderate language deficits.European child & adolescent psychiatry · 2025Article
- Associations between telomere length, glucocorticoid receptor gene DNA methylation, volume of stress-related brain structures, and academic performance in middle-school-age children.Comprehensive psychoneuroendocrinology · 2024Article
- Insights into the structure and function of the hippocampus: implications for the pathophysiology and treatment of autism spectrum disorder.Frontiers in psychiatry · 2024Review
- Volumetric development of hippocampal subfields and hippocampal white matter connectivity: Relationship with episodic memory.Developmental psychobiology · 2022Article
- Activation for newly learned words in left medial-temporal lobe during toddlers' sleep is associated with memory for words.Current biology : CB · 2021Article
- The Role of Sleep in Retention of New Words in Habitually and Non-Habitually Napping Children.Brain sciences · 2021Article
- Automatic multispectral MRI segmentation of human hippocampal subfields: an evaluation of multicentric test-retest reproducibility.Brain structure & function · 2021Article
- Understanding Hippocampal Development in Young Children With Autism Spectrum Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2020Article
- Children's family income is associated with cognitive function and volume of anterior not posterior hippocampus.Nature communications · 2020Article
- Growing up with interfering neighbours: the influence of time of learning and vocabulary knowledge on written word learning in children.Royal Society open science · 2020Article
- Empirical Evidence Supporting Neural Contributions to Episodic Memory Development in Early Childhood: Implications for Childhood Amnesia.Child development perspectives · 2020Article
- Changes in anterior and posterior hippocampus differentially predict item-space, item-time, and item-item memory improvement.Developmental cognitive neuroscience · 2020Article
- Learning to live with interfering neighbours: the influence of time of learning and level of encoding on word learning.Royal Society open science · 2019Article
- Relations between neural structures and children's self-derivation of new knowledge through memory integration.Developmental cognitive neuroscience · 2019Article
- When two are better than one: Bilateral mesial temporal lobe contributions associated with better vocabulary skills in children and adolescents.Brain and language · 2018Article
- Protracted hippocampal development is associated with age-related improvements in memory during early childhood.NeuroImage · 2018Article
- Memory-related hippocampal activation in the sleeping toddler.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Serum ApoB levels in depressive patients: associated with cognitive deficits.Scientific reports · 2017Article
Corrections and comments
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6 authors.
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Abstract
Volumetric assessments of the hippocampus and other brain structures during childhood provide useful indices of brain development and correlates of cognitive functioning in typically and atypically developing children. Automated methods such as FreeSurfer promise efficient and replicable segmentation, but may include errors which are avoided by trained manual tracers. A recently devised automated correction tool that uses a machine learning algorithm to remove systematic errors, the Automatic Segmentation Adapter Tool (ASAT), was capable of substantially improving the accuracy of FreeSurfer segmentations in an adult sample [Wang et al., 2011], but the utility of ASAT has not been examined in pediatric samples. In Study 1, the validity of FreeSurfer and ASAT corrected hippocampal segmentations were examined in 20 typically developing children and 20 children with autism spectrum disorder aged 2 and 3 years. We showed that while neither FreeSurfer nor ASAT accuracy differed by disorder or age, the accuracy of ASAT corrected segmentations were substantially better than FreeSurfer segmentations in every case, using as few as 10 training examples. In Study 2, we applied ASAT to 89 typically developing children aged 2 to 4 years to examine relations between hippocampal volume, age, sex, and expressive language. Girls had smaller hippocampi overall, and in left hippocampus this difference was larger in older than younger girls. Expressive language ability was greater in older children, and this difference was larger in those with larger hippocampi, bilaterally. Overall, this research shows that ASAT is highly reliable and useful to examinations relating behavior to hippocampal structure.
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