ArticleAmerican journal of respiratory and critical care medicine2015
An Official American Thoracic Society Research Statement: A Research Framework for Pulmonary Nodule Evaluation and Management.
Article in American journal of respiratory and critical care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Three-dimensionally printed navigational template technology for lung biopsy: a noninferiority, randomized trial.International journal of surgery (London, England) · 2026Trial
- Real-World Imaging Data: Opportunities and Challenges.JMIR medical informatics · 2026Article
- Development of a Pulmonary Nodule Service and Clinical Pathway: A Pragmatic Approach Addressing an Unmet Need.Diagnostics (Basel, Switzerland) · 2025Article
- Radiomics and artificial intelligence for risk stratification of pulmonary nodules: Ready for primetime?Cancer biomarkers : section A of Disease markers · 2025Review
- Article
- Indeterminate pulmonary nodules and prior malignancy: survival and recurrence after surgery in newly diagnosed stage I non-small cell lung cancer.Journal of thoracic disease · 2024Article
- Factors influencing surgical choice and anxiety in patients with pulmonary nodules smaller than 8 mm.Journal of thoracic disease · 2023Article
- The Effect of a Dedicated Lung Mass Clinic on Lung Nodule Follow Up.Annals of public health & epidemiology · 2022Article
- Systemic Profiles of microRNAs, Redox Balance, and Inflammation in Lung Cancer Patients: Influence of COPD.Biomedicines · 2021Article
- The LungVision navigational platform for peripheral lung nodule biopsy and the added value of cryobiopsy.Thoracic cancer · 2021Article
- Article
- Observational
- B Cells and Tertiary Lymphoid Structures Influence Survival in Lung Cancer Patients with Resectable Tumors.Cancers · 2020Article
- Article
- Follow-up of incidental pulmonary nodules and association with mortality in a safety-net cohort.Diagnosis (Berlin, Germany) · 2019Article
- Pulmonary Nodules: A Small Problem for Many, Severe Distress for Some, and How to Communicate About It.Chest · 2018Review
- Napsin A levels in epithelial lining fluid as a diagnostic biomarker of primary lung adenocarcinoma.BMC pulmonary medicine · 2017Article
- The pulmonary nodule "discovered" by pneumonia: a case report.Translational lung cancer research · 2017Article
- Update in Lung Cancer 2015.American journal of respiratory and critical care medicine · 2016Article
- Systems-Level Resources for Pulmonary Nodule Evaluation in the United States: A National Survey.American journal of respiratory and critical care medicine · 2016Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundPulmonary nodules are frequently detected during diagnostic chest imaging and as a result of lung cancer screening. Current guidelines for their evaluation are largely based on low-quality evidence, and patients and clinicians could benefit from more research in this area.
methodsIn this research statement from the American Thoracic Society, a multidisciplinary group of clinicians, researchers, and patient advocates reviewed available evidence for pulmonary nodule evaluation, characterized six focus areas to direct future research efforts, and identified fundamental gaps in knowledge and strategies to address them. We did not use formal mechanisms to prioritize one research area over another or to achieve consensus.
resultsThere was widespread agreement that novel tests (including novel imaging tests and biopsy techniques, biomarkers, and prognostic models) may improve diagnostic accuracy for identifying cancerous nodules. Before they are used in clinical practice, however, better evidence is needed to show that they improve more distal outcomes of importance to patients. In addition, the pace of research and the quality of clinical care would be improved by the development of registries that link demographic and nodule characteristics with patient-level outcomes. Methods to share data from registries are also necessary.
conclusionsThis statement may help researchers to develop impactful and innovative research projects and enable funders to better judge research proposals. We hope that it will accelerate the pace and increase the efficiency of discovery to improve the quality of care for patients with pulmonary nodules.
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