Evidence map›Paper›PMID 26277798›Full record

ArticleEmerging infectious diseases2015

Chronic Q fever diagnosis— consensus guideline versus expert opinion

Linda M Kampschreur, Marjolijn C A Wegdam-Blans, Peter C Wever, Nicole H M Renders, Corine E Delsing, Tom Sprong, Marjo E E van Kasteren, Henk Bijlmer, Daan Notermans, Jan Jelrik Oosterheert and 4 more

Open access · diamondAbstract readComparative Study
In one paragraph

Article in Emerging infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.

  1. A systematic review on the health outcomes associated with non-endocarditis manifestations of chronic Q fever.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Pooled it
  2. Plasma microbial cell-free DNA sequencing for detection ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2026
    Article
  3. Spinal infection caused byFrontiers in medicine · 2026
    Article
  4. Article
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  6. VirCliaEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Frontiers in medicine · 2025
    Article
  12. Frontiers in immunology · 2025
    Article
  13. Article
  14. Case Report:Frontiers in medicine · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. The integration ofJournal of clinical microbiology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Linda M Kampschreur
Marjolijn C A Wegdam-Blans
Peter C Wever
Nicole H M Renders
Corine E Delsing
Tom Sprong
Marjo E E van Kasteren
Henk Bijlmer
Daan Notermans
Jan Jelrik Oosterheert
Frans S Stals
Marrigje H Nabuurs-Franssen
Chantal P Bleeker-Rovers
Dutch Q Fever Consensus Group
Radboud University Nijmegen · NLCanisius-Wilhelmina Ziekenhuis · NLElisabeth-TweeSteden Ziekenhuis · NLNational Institute for Public Health and the Environment · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic Q fever, caused by Coxiella burnetii, has high mortality and morbidity rates if left untreated. Controversy about the diagnosis of this complex disease has emerged recently. We applied the guideline from the Dutch Q Fever Consensus Group and a set of diagnostic criteria proposed by Didier Raoult to all 284 chronic Q fever patients included in the Dutch National Chronic Q Fever Database during 2006–2012. Of the patients who had proven cases of chronic Q fever by the Dutch guideline, 46 (30.5%)would not have received a diagnosis by the alternative criteria designed by Raoult, and 14 (4.9%) would have been considered to have possible chronic Q fever. Six patients with proven chronic Q fever died of related causes. Until results from future studies are available, by which current guidelines can be modified, we believe that the Dutch literature-based consensus guideline is more sensitive and easier to use in clinical practice.

Indexed as

HumansNetherlandsPractice Guidelines as TopicQ Fever

Identifiers

PMID26277798
PMCPMC4480373
OpenAlexW2412340160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.