Trial reportBehaviour research and therapy2015
Can adaptive treatment improve outcomes in family-based therapy for adolescents with anorexia nervosa? Feasibility and treatment effects of a multi-site treatment study.
Trial report in Behaviour research and therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Efficacy of Eating Disorder Focused Family Therapy for Adolescents With Anorexia Nervosa: A Systematic Review and Meta-Analysis.The International journal of eating disorders · 2025Pooled it
- A systematic review of the impact of carer interventions on outcomes for patients with eating disorders.Eating and weight disorders : EWD · 2022Pooled it
- Gender-based clinical differences in evidence-based treatment for adolescent anorexia nervosa: analysis of aggregated randomized controlled trials.Eating and weight disorders : EWD · 2022Pooled it
- Family therapy approaches for anorexia nervosa.The Cochrane database of systematic reviews · 2019Pooled it
- Statistical design and analysis in trials of proportionate interventions: a systematic review.Trials · 2019Pooled it
- Family therapy approaches for anorexia nervosa.The Cochrane database of systematic reviews · 2018Pooled it
- The Impact of Emotion Coaching on Changes in Caregiver Burden and Distress Tolerance During Family-Based Treatment.The International journal of eating disorders · 2026Trial
- Who Responds to an Adaptive Intervention for Adolescents With Anorexia Nervosa Being Treated With Family-Based Treatment? Outcomes From a Randomized Clinical Trial.Journal of the American Academy of Child and Adolescent Psychiatry · 2024Trial
- Predictors of family-based treatment for adolescent eating disorders: Do family or diagnostic factors matter?The International journal of eating disorders · 2023Trial
- Randomized Clinical Trial of Family-Based Treatment and Cognitive-Behavioral Therapy for Adolescent Bulimia Nervosa.Journal of the American Academy of Child and Adolescent Psychiatry · 2015Trial
- When Is the Right Time to End Family Therapy for Anorexia Nervosa (FT-AN)?: A Qualitative Study of Young People's Experiences.European eating disorders review : the journal of the Eating Disorders Association · 2026Article
- Predicting adolescent disordered eating and behaviours: exploring environmental moderators of polygenic risk.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Comparing Outcomes for Telehealth Versus In-Person Family-Based Treatment: A Retrospective Chart Review.The International journal of eating disorders · 2025Article
- Mother-Father Distress, Accommodation, and Child Eating Disorder Behaviors: A Dyadic Perspective.Family process · 2025Article
- Effects of Early Weight Trends on Residential Treatment Outcomes Among Adolescents With Anorexia Nervosa.The International journal of eating disorders · 2025Article
- Psychotherapies for eating disorders: findings from a rapid review.Journal of eating disorders · 2023Review
- The assessment of caregiver self-efficacy in a virtual eating disorder setting.Journal of eating disorders · 2023Article
- Effects of family-based treatment on adolescent outpatients treated for anorexia nervosa in the Eating Disorder Unit of Helsinki University Hospital.Journal of eating disorders · 2023Article
- Adapting family-based treatment for adolescent anorexia nervosa delivered in the home: A novel approach for improving access to care and generalizability of skill acquisition.Journal of eating disorders · 2023Article
- How best to support parents of children with an eating disorder: A commentary on Wilksch (2023).The International journal of eating disorders · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectiveAdolescents with Anorexia Nervosa (AN), treated with family-based treatment (FBT) who fail to gain 2.3 kg by the fourth week of treatment have a 40-50% lower chance of recovery than those who do. Because of the high risk of developing enduring AN, improving outcomes in this group of poor responders is essential. This study examines the feasibility and effects of a novel adaptive treatment (i.e., Intensive Parental Coaching-IPC) aimed at enhancing parental self-efficacy related to re-feeding skills in poor early responders to FBT.
method45 adolescents (12-18 years of age) meeting DSM TR IV criteria for AN were randomized in an unbalanced design (10 to standard FBT; 35 to the adaptive arm). Attrition, suitability, expectancy rates, weight change, and psychopathology were compared between groups. OUTCOMES: There were no differences in rates of attrition, suitability, expectancy ratings, or most clinical outcomes between randomized groups. However, the group of poor early responders that received IPC achieved full weight restoration (>95% of expected mean BMI) by EOT at similar rates as those who had responded early.
conclusionsThe results of this study suggest that it is feasible to use an adaptive design to study the treatment effect of IPC for those who do not gain adequate weight by session 4 of FBT. The results also suggest that using IPC for poor early responders significantly improves weight recovery rates to levels comparable to those who respond early. A sufficiently powered study is needed to confirm these promising findings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.