Evidence map›Paper›PMID 26276624›Full record

ArticleCell2015

An AAA+ ATPase Clamshell Targets Transposition.

Chi-Lin Tsai, Gareth J Williams, J Jefferson P Perry, John A Tainer

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Chi-Lin TsaiLife Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Gareth J WilliamsLife Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
J Jefferson P PerryDepartment of Biochemistry, University of California, Riverside, Riverside, CA 92521, USA.
John A TainerLife Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA; Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: jatainer@lbl.gov.

Funding

Transcription-Coupled & Replication-Associated Excision RepairP01CA092584 · NCI · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI John A. Tainer · 2001 to 2026
$89.6M
Defining RAD51 paralog complexes to inform their roles in genome maintenanceR21ES025895 · NIEHS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI WILLIAMS, GARETH J · 2015 to 2016
$430k
NCI NIH HHS P01 CA092584NIEHS NIH HHS R21 ES025895NIEHS NIH HHS R21ES025895
6 · The paper itself

Abstract

DNA transposition plays key roles in genome diversity, pathogenesis, and evolution. Yet, structural and mechanistic information on transposition targeting and regulation is limited. Arias-Palomo and Berger now define the decameric organization of the AAA+ ATPase IstB, unveiling key insights into its targeting and regulation of IstA transposase activity.

Indexed as

DNA Transposable ElementsBacteriaDNA Transposable Elements

Identifiers

PMID26276624
PMCPMC5550827

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.