ArticleBMC veterinary research2015
Detection of serum neutralizing antibodies to Simbu sero-group viruses in cattle in Tanzania.
Article in BMC veterinary research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Serological prevalence of the Schmallenberg virus in domestic and wild hosts worldwide: a systematic review and meta-analysis.Frontiers in veterinary science · 2024Pooled it
- Role of vimentin in inhibiting akabane virus replication and its preliminary exploration of mechanisms involving autophagy and apoptosis.BMC veterinary research · 2026Article
- The Dynamic Transmission of Simbu Group Viruses in New South Wales, Australia.Transboundary and emerging diseases · 2026Article
- A serological study and risk factors associated with Akabane virus infection in cattle in Egypt.Scientific reports · 2025Article
- Investigating serological evidence of Schmallenberg virus in cattle in eastern Algeria.Veterinary research forum : an international quarterly journal · 2025Article
- Article
- The First Serological Detection and Risk Factors Analysis of Akabane Virus in Egyptian Cattle.Animals : an open access journal from MDPI · 2023Article
- First detection of Schmallenberg virus antibody in cattle population of eastern Iran.Veterinary research forum : an international quarterly journal · 2022Article
- Examining bull semen for residues of Schmallenberg virus RNA.Transboundary and emerging diseases · 2022Article
- Differentiation of Antibodies against Selected Simbu Serogroup Viruses by a Glycoprotein Gc-Based Triplex ELISA.Veterinary sciences · 2021Article
- Shuni Virus in Wildlife and Nonequine Domestic Animals, South Africa.Emerging infectious diseases · 2020Article
- Prevalence of Antibodies to Simbu Serogroup Viruses in Cattle in Sudan.Veterinary medicine international · 2020Article
- Comparative evaluation of two commercial ELISA kits for detection of antibodies against Akabane virus in cattle serum.BMC veterinary research · 2019Article
- First genomic detection of Peaton virus in a calf with hydranencephaly in Israel.Veterinary medicine and science · 2019Article
- Schmallenberg virus: a systematic international literature review (2011-2019) from an Irish perspective.Irish veterinary journal · 2019Review
- Host-dependence of in vitro reassortment dynamics among the Sathuperi and Shamonda Simbuviruses.Emerging microbes & infections · 2019Article
- Congenital abnormalities in calves associated with Peaton virus infection in Japan.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2018Article
- Neutralizing antibodies against Simbu serogroup viruses in cattle and sheep, Nigeria, 2012-2014.BMC veterinary research · 2018Article
- Endemic and emerging arboviral diseases of livestock in Nigeria: a review.Parasites & vectors · 2018Review
- Preliminary serological evidence for Schmallenberg virus infection in China.Tropical animal health and production · 2018Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOrthobunyaviruses belonging to the Simbu sero-group occur worldwide, including the newly recognized Schmallenberg virus (SBV) in Europe. These viruses cause congenital malformations and reproductive losses in ruminants. Information on the presence of these viruses in Africa is scarce and the origin of SBV is unknown. The aim of this study was to investigate the presence of antibodies against SBV and closely related viruses in cattle in Tanzania, and their possible association with reproductive disorders.
resultsIn a cross-sectional study, serum from 659 cattle from 202 herds collected in 2012/2013 were analyzed using a commercial kit for SBV ELISA, and 61 % were positive. Univariable logistic regression revealed significant association between ELISA seropositivity and reproductive disorders (OR = 1.9). Sera from the same area collected in 2008/2009, before the SBV epidemic in Europe, were also tested and 71 (54.6 %) of 130 were positive. To interpret the ELISA results, SBV virus neutralization test (VNT) was performed on 110 sera collected in 2012/2013, of which 51 % were positive. Of 71 sera from 2008/2009, 21 % were positive. To investigate potential cross reactivity with related viruses, 45 sera from 2012/2013 that were positive in SBV ELISA were analyzed in VNTs for Aino, Akabane, Douglas, Peaton, Sabo, SBV, Sathuperi, Shamonda, Simbu and Tinaroo viruses. All 45 sera were positive for one or more of these viruses. Twenty-nine sera (64.4 %) were positive for SBV, and one had the highest titer for this virus.
conclusionsThis is the first indication that Aino, Akabane, Douglas, Peaton, Sabo, SBV, Sathuperi, Shamonda and Tinaroo viruses circulate and cause negative effect on reproductive performance in cattle in Tanzania. SBV or a closely related virus was present before the European epidemic. However, potential cross reactivity complicates the interpretation of serological studies in areas where several related viruses may circulate. Virus isolation and molecular characterization in cattle and/or vectors is recommended to further identify the viruses circulating in this region. However, isolation in cattle is difficult due to short viremic period of 2 to 6 days, and isolation in vectors does not necessarily reflect the situation in cattle.
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