Evidence map›Paper›PMID 26276380›Full record

ArticleNeurology2015

The unruptured intracranial aneurysm treatment score: a multidisciplinary consensus.

Nima Etminan, Robert D Brown, Kerim Beseoglu, Seppo Juvela, Jean Raymond, Akio Morita, James C Torner, Colin P Derdeyn, Andreas Raabe, J Mocco and 61 more

Open access · bronzeAbstract readConsensus Statement
In one paragraph

Article in Neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 165 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
165citing papers in PubMed, 5 pooled it
22.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

165 citing papers in PubMed, 5 syntheses or guidelines pooled it, 396 citations in OpenAlex.

  1. Pooled it
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  17. Investigation of Contrast Retention in PCOM Aneurysms as a Possible Marker for Instability and Rupture.International journal for numerical methods in biomedical engineering · 2026
    Article
  18. Morphological characteristics of brain aneurysms among age groups.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  19. Article
  20. Article

105 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

71 authors at 1 institution in 1 country.

Nima EtminanAuthor affiliations are provided at the end of the article. etminan@uni-duesseldorf.de.
Robert D BrownAuthor affiliations are provided at the end of the article.
Kerim BeseogluAuthor affiliations are provided at the end of the article.
Seppo JuvelaAuthor affiliations are provided at the end of the article.
Jean RaymondAuthor affiliations are provided at the end of the article.
Akio MoritaAuthor affiliations are provided at the end of the article.
James C TornerAuthor affiliations are provided at the end of the article.
Colin P DerdeynAuthor affiliations are provided at the end of the article.
Andreas RaabeAuthor affiliations are provided at the end of the article.
J MoccoAuthor affiliations are provided at the end of the article.
Miikka KorjaAuthor affiliations are provided at the end of the article.
Amr AbdulazimAuthor affiliations are provided at the end of the article.
Sepideh Amin-HanjaniAuthor affiliations are provided at the end of the article.
Rustam Al-Shahi SalmanAuthor affiliations are provided at the end of the article.
Daniel L BarrowAuthor affiliations are provided at the end of the article.
Joshua BedersonAuthor affiliations are provided at the end of the article.
Alain BonafeAuthor affiliations are provided at the end of the article.
Aaron S DumontAuthor affiliations are provided at the end of the article.
David J FiorellaAuthor affiliations are provided at the end of the article.
Andreas GruberAuthor affiliations are provided at the end of the article.
Graeme J HankeyAuthor affiliations are provided at the end of the article.
David M HasanAuthor affiliations are provided at the end of the article.
Brian L HohAuthor affiliations are provided at the end of the article.
Pascal JabbourAuthor affiliations are provided at the end of the article.
Hidetoshi KasuyaAuthor affiliations are provided at the end of the article.
Michael E KellyAuthor affiliations are provided at the end of the article.
Peter J KirkpatrickAuthor affiliations are provided at the end of the article.
Neville KnuckeyAuthor affiliations are provided at the end of the article.
Timo KoivistoAuthor affiliations are provided at the end of the article.
Timo KringsAuthor affiliations are provided at the end of the article.
Michael T LawtonAuthor affiliations are provided at the end of the article.
Thomas R MarottaAuthor affiliations are provided at the end of the article.
Stephan A MayerAuthor affiliations are provided at the end of the article.
Edward MeeAuthor affiliations are provided at the end of the article.
Vitor Mendes PereiraAuthor affiliations are provided at the end of the article.
Andrew MolyneuxAuthor affiliations are provided at the end of the article.
Michael K MorganAuthor affiliations are provided at the end of the article.
Kentaro MoriAuthor affiliations are provided at the end of the article.
Yuichi MurayamaAuthor affiliations are provided at the end of the article.
Shinji NagahiroAuthor affiliations are provided at the end of the article.
Naoki NakayamaAuthor affiliations are provided at the end of the article.
Mika NiemeläAuthor affiliations are provided at the end of the article.
Christopher S OgilvyAuthor affiliations are provided at the end of the article.
Laurent PierotAuthor affiliations are provided at the end of the article.
Alejandro A RabinsteinAuthor affiliations are provided at the end of the article.
Yvo B W E M RoosAuthor affiliations are provided at the end of the article.
Jaakko RinneAuthor affiliations are provided at the end of the article.
Robert H RosenwasserAuthor affiliations are provided at the end of the article.
Antti RonkainenAuthor affiliations are provided at the end of the article.
Karl SchallerAuthor affiliations are provided at the end of the article.
Volker SeifertAuthor affiliations are provided at the end of the article.
Robert A SolomonAuthor affiliations are provided at the end of the article.
Julian SpearsAuthor affiliations are provided at the end of the article.
Hans-Jakob SteigerAuthor affiliations are provided at the end of the article.
Mervyn D I VergouwenAuthor affiliations are provided at the end of the article.
Isabel WankeAuthor affiliations are provided at the end of the article.
Marieke J H WermerAuthor affiliations are provided at the end of the article.
George K C WongAuthor affiliations are provided at the end of the article.
John H WongAuthor affiliations are provided at the end of the article.
Gregory J ZipfelAuthor affiliations are provided at the end of the article.
E Sander ConnollyAuthor affiliations are provided at the end of the article.
Helmuth SteinmetzAuthor affiliations are provided at the end of the article.
Giuseppe LanzinoAuthor affiliations are provided at the end of the article.
Alberto PasqualinAuthor affiliations are provided at the end of the article.
Daniel RüfenachtAuthor affiliations are provided at the end of the article.
Peter VajkoczyAuthor affiliations are provided at the end of the article.
Cameron McDougallAuthor affiliations are provided at the end of the article.
Daniel HänggiAuthor affiliations are provided at the end of the article.
Peter LeRouxAuthor affiliations are provided at the end of the article.
Gabriel J E RinkelAuthor affiliations are provided at the end of the article.
R Loch MacdonaldAuthor affiliations are provided at the end of the article.
School of the Art Institute of Chicago · US

Funding

Medical Research Council G1002605Medical Research Council G108/613
6 · The paper itself

Abstract

objectiveWe endeavored to develop an unruptured intracranial aneurysm (UIA) treatment score (UIATS) model that includes and quantifies key factors involved in clinical decision-making in the management of UIAs and to assess agreement for this model among specialists in UIA management and research.

methodsAn international multidisciplinary (neurosurgery, neuroradiology, neurology, clinical epidemiology) group of 69 specialists was convened to develop and validate the UIATS model using a Delphi consensus. For internal (39 panel members involved in identification of relevant features) and external validation (30 independent external reviewers), 30 selected UIA cases were used to analyze agreement with UIATS management recommendations based on a 5-point Likert scale (5 indicating strong agreement). Interrater agreement (IRA) was assessed with standardized coefficients of dispersion (vr*) (vr* = 0 indicating excellent agreement and vr* = 1 indicating poor agreement).

resultsThe UIATS accounts for 29 key factors in UIA management. Agreement with UIATS (mean Likert scores) was 4.2 (95% confidence interval [CI] 4.1-4.3) per reviewer for both reviewer cohorts; agreement per case was 4.3 (95% CI 4.1-4.4) for panel members and 4.5 (95% CI 4.3-4.6) for external reviewers (p = 0.017). Mean Likert scores were 4.2 (95% CI 4.1-4.3) for interventional reviewers (n = 56) and 4.1 (95% CI 3.9-4.4) for noninterventional reviewers (n = 12) (p = 0.290). Overall IRA (vr*) for both cohorts was 0.026 (95% CI 0.019-0.033).

conclusionsThis novel UIA decision guidance study captures an excellent consensus among highly informed individuals on UIA management, irrespective of their underlying specialty. Clinicians can use the UIATS as a comprehensive mechanism for indicating how a large group of specialists might manage an individual patient with a UIA.

Indexed as

InternationalityInterprofessional RelationsSeverity of Illness IndexHumansIntracranial AneurysmPatient Care TeamTreatment Outcome

Identifiers

PMID26276380
PMCPMC4560059
OpenAlexW2171541197

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.