Evidence map›Paper›PMID 26276246›Full record

ArticleContraception2015

Meaning-making matters in product design: users' sensory perceptions and experience evaluations of long-acting vaginal gels and intravaginal rings.

Rochelle K Rosen, Jacob J van den Berg, Sara E Vargas, Natali Senocak, Julia G Shaw, Robert W Buckheit, Kelley Alison Smith, Kate Morrow Guthrie

Abstract read
In one paragraph

Article in Contraception, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rochelle K RosenCenters for Behavioral and Preventive Medicine, The Miriam Hospital, Coro West, Suite 309, 164 Summit Avenue, Providence, RI 02906, USA; Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI 02906, USA. Electronic address: rrosen@lifespan.org.
Jacob J van den BergCenters for Behavioral and Preventive Medicine, The Miriam Hospital, Coro West, Suite 309, 164 Summit Avenue, Providence, RI 02906, USA; Department of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USA. Electronic address: jvandenberg@lifespan.org.
Sara E VargasCenters for Behavioral and Preventive Medicine, The Miriam Hospital, Coro West, Suite 309, 164 Summit Avenue, Providence, RI 02906, USA; Department of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USA. Electronic address: svargas@lifespan.org.
Natali SenocakCenters for Behavioral and Preventive Medicine, The Miriam Hospital, Coro West, Suite 309, 164 Summit Avenue, Providence, RI 02906, USA. Electronic address: natalisenocak@gmail.com.
Julia G ShawCenters for Behavioral and Preventive Medicine, The Miriam Hospital, Coro West, Suite 309, 164 Summit Avenue, Providence, RI 02906, USA. Electronic address: julia.shaw@gmail.com.
Robert W BuckheitImQuest BioSciences, Inc., 7340 Executive Way, Suite R, Frederick, MD 21704, USA. Electronic address: rbuckheit@imquestbio.com.
Kelley Alison SmithCenters for Behavioral and Preventive Medicine, The Miriam Hospital, Coro West, Suite 309, 164 Summit Avenue, Providence, RI 02906, USA. Electronic address: ksmith20@lifespan.org.
Kate Morrow GuthrieCenters for Behavioral and Preventive Medicine, The Miriam Hospital, Coro West, Suite 309, 164 Summit Avenue, Providence, RI 02906, USA; Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI 02906, USA; Department of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USA. Electronic address: kmorrow@lifespan.org.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
Using Coincidence Analysis to Investigate Factors Affecting PrEP Initiation and Continuation in Southern ending the Epidemic CountiesP30MH062294 · NIMH · YALE UNIVERSITY · PI John Edward Pachankis · 2001 to 2026
$48.5M
Preclinical User Accptability Studies Long Acting Vaginal Gels, Intravaginal RingU19AI077289 · NIAID · IMQUEST BIOSCIENCES · PI KISER, PATRICK FRANKLIN · 2008 to 2012
$6.7M
Advancing Reproductive Health: Qualitative Methods & Interdisciplinary MentorshipK24HD062645 · NICHD · MIRIAM HOSPITAL · PI GUTHRIE, KATE M · 2012 to 2016
$689k
NIAID NIH HHS P30 AI042853NIAID NIH HHS U19 AI077289NIAID NIH HHS U19AI077289NICHD NIH HHS K24 HD062645NIMH NIH HHS P30 MH062294
6 · The paper itself

Abstract

objectiveUsers' sensory perceptions and experiences of intravaginal products can inform acceptability and adherence. Focusing on the meanings women derive from formulation/device characteristics facilitates developers' design iterations toward optimizing user experience. We investigated how users of long-acting gels and intravaginal rings (IVRs) impute meaning to characteristics that may affect future product use. STUDY

designFocus groups were conducted with contraceptive IVR and vaginal lubricant users. Current perceptibility science and historical theory on the cultural acceptability of fertility regulating methods informed the analysis.

resultsA total of 21 IVR users and 29 lubricant users attended focus groups in which they manipulated products in their hands and discussed reactions to product characteristics. Participants used prior product experiences and sensory perceptions of prototype manipulations to inform meanings about product properties and performance for pregnancy, disease prevention, comfort, and perceived efficacy. The meanings derived from product characteristics depended on why the product would be used; a characteristic deemed problematic in one risk context may be considered preferable in another.

conclusionsIntravaginal product users create narratives that ascribe influence or causality to product characteristics. These meanings, whether correct or incorrect biologically, will shape vaginal product acceptability, use, and effectiveness. IMPLICATIONS: Long-acting and sustained-release drug delivery systems will be part of the multipurpose prevention continuum. Developers must consider how sensory experiences and culturally salient assumptions shape the meanings users make of product design characteristics. Those meanings will ultimately impact use and effectiveness.

Indexed as

Contraceptive Devices, FemaleAdministration, IntravaginalAdultContraceptionContraception BehaviorEquipment DesignFemaleFocus GroupsHumansPatient Acceptance of Health CareSpermatocidal AgentsVaginal Creams, Foams, and JelliesSpermatocidal AgentsVaginal Creams, Foams, and JelliesIntravaginal ringMeaning-makingMicrobicidesMultipurpose prevention technologiesSTI preventionVaginal gel

Identifiers

PMID26276246
PMCPMC4664151

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.