Trial reportEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2015
Local infiltration analgesia versus continuous interscalene brachial plexus block for shoulder replacement pain: a randomized clinical trial.
Trial report in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effective Pain Management During Shoulder Replacement Surgery With Either Continuous Ropivacaine Interscalene Nerve Block or Local Infiltration With EXPAREL After Single Shot Injection Ropivacaine Interscalene Nerve Block
Local Infiltration Analgesia Vs. Interscalene Block in Total Shoulder Arthorplasty: A Randomized Controlled Trial
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Postoperative neurologic symptoms in the operative arm after shoulder surgery with interscalene blockade: a systematic review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022Pooled it
- Liposomal bupivacaine nerve block provides better pain control post-total shoulder arthroplasty than continuous indwelling catheter.Archives of orthopaedic and trauma surgery · 2023Trial
- Comparison of local infiltration analgesia and interscalene block for postoperative pain management in shoulder arthroscopy: a prospective randomized controlled trialTurkish journal of medical sciences · 2021Trial
- A comparison of ice wrap and subacromial injection for postoperative pain and edema control following arthroscopic rotator cuff repair.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2020Trial
- Effect of postoperative NSAID use on opioid consumption after rotator cuff repair.Journal of orthopaedics · 2025Article
- Postoperative pain control for shoulder arthroplasty.Clinics in shoulder and elbow · 2024Article
- Optimal analgesic regimen for total shoulder arthroplasty: a randomized controlled trial and network meta-analysis.Journal of orthopaedic surgery and research · 2024Article
- Beware the rebound effect: regional anesthesia increases opioid utilization after humerus fracture surgery.Shoulder & elbow · 2022Article
- Narcotic requirements after shoulder arthroplasty are low using a multimodal approach to pain.JSES international · 2021Article
- Efficacy of local infiltration anesthesia versus interscalene nerve blockade for total shoulder arthroplasty.JSES international · 2020Article
- Single-Shot Versus Continuous Interscalene Block for Postoperative Pain Control After Shoulder Arthroplasty: A Prospective Randomized Clinical Trial.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2019Article
- Acute postoperative pain after arthroscopic rotator cuff surgery: A review of methods of pain assessment.SICOT-J · 2018Article
- The effect of local/topical analgesics on incisional pain in a pig model.Journal of pain research · 2017Article
- The efficacy and safety of continuous transmuscular quadratus lumborum block for postoperative analgesia after laparoscopic nephrectomy: A prospective randomized clinical trial.Journal of anaesthesiology, clinical pharmacologyArticle
- Prospective study of ultrasound-guided peri-plexus interscalene block with continuous infusion catheter for arthroscopic rotator cuff repair and postoperative pain control.Revista brasileira de ortopediaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundShoulder replacement involves significant post-operative pain, which is often managed by continuous interscalene brachial plexus block. Catheter displacement and complications limit the beneficial effect of the block. Local infiltration analgesia (LIA) has provided good results in knee replacement. We aimed to assess the effectiveness of LIA for pain after shoulder replacement.
methodsPatients scheduled for primary shoulder replacement under general anaesthesia were randomized to receive either local infiltration analgesia (LIA) (150 ml ropivacaine 0.2 % with epinephrine intra-operatively) or interscalene brachial plexus catheter (ISC) (ropivacaine 0.75 %, 7 ml bolus followed by 48-h 5 ml/h infusion). The primary outcome was opioid consumption during the first 24 post-operative hours. Secondary outcomes were pain ratings, supplementary analgesics, and side effects for 3 days, and complications until 3 months after surgery.
resultsData were analysed for 61 patients (LIA 30, ISC 31). Twenty-four-hour opioid consumption was higher in the LIA group compared with the ISC group: median (IQR) 95 mg (70-150 mg) versus 40 mg (8-76 mg) (P = 0.0001). No significant difference in opioid consumption was found between groups during the following 3 days. The LIA group had higher pain scores at 0, 2, 4, and 8 h. Two patients in the ISC group had long-lasting complications.
conclusionsThe LIA technique cannot be recommended for shoulder replacement unless substantially modified. Occurrence of inadequate analgesia and complications following interscalene brachial plexus block prompt further studies into pain management after shoulder replacement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.