Evidence map›Paper›PMID 26276052›Full record

ArticleEnvironmental health : a global access science source2015

Repeated measures of inflammation, blood pressure, and heart rate variability associated with traffic exposures in healthy adults.

Jaime E Mirowsky, Richard E Peltier, Morton Lippmann, George Thurston, Lung-Chi Chen, Lucas Neas, David Diaz-Sanchez, Robert Laumbach, Jacqueline D Carter, Terry Gordon

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Environmental and Occupational Short-Term Exposure to Airborne Particles and FEVInternational journal of environmental research and public health · 2021
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Increased Outdoor PMJournal of environmental and public health · 2019
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Residential Proximity to Major Roadways and Risk of Type 2 Diabetes Mellitus: A Meta-Analysis.International journal of environmental research and public health · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Jaime E MirowskyDepartment of Environmental Medicine, New York University, Tuxedo, NY, USA. mirowsky@email.unc.edu.
Richard E PeltierDivision of Environmental Health Science, University of Massachusetts, Amherst, MA, USA. rpeltier@schoolph.umass.edu.
Morton LippmannDepartment of Environmental Medicine, New York University, Tuxedo, NY, USA. Morton.Lippmann@nyumc.org.
George ThurstonDepartment of Environmental Medicine, New York University, Tuxedo, NY, USA. george.thurston@nyu.edu.
Lung-Chi ChenDepartment of Environmental Medicine, New York University, Tuxedo, NY, USA. Lung-Chi.Chen@nyumc.org.
Lucas NeasU.S. EPA; Epidemiology Branch, Chapel Hill, NC, USA. neas.lucas@epa.gov.
David Diaz-SanchezU.S. EPA; Environmental Public Health Division, Chapel Hill, NC, USA. diaz-sanchez.david@epa.gov.
Robert LaumbachDepartment of Environmental and Occupational Medicine, University of Medicine and Dentistry of New Jersey, Piscataway, NJ, USA. laumbach@eohsi.rutgers.edu.
Jacqueline D CarterU.S. EPA; Environmental Public Health Division, Chapel Hill, NC, USA. carter.jackie@epa.gov.
Terry GordonDepartment of Environmental Medicine, New York University, Tuxedo, NY, USA. Terry.Gordon@nyumc.org.
Environmental Protection Agency · USNew York University · USTisch Hospital · USCity University of New York · USRutgers, The State University of New Jersey · USUniversity of Massachusetts Amherst · US

Funding

RESEARCH IN ENVIRONMENTAL HEALTH SCIENCES (CENTER GRANT)P30ES000260 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COSTA, MAX · 1985 to 2020
$26.1M
TRAINING PROGRAM IN ENVIRONMENTAL TOXICOLOGYT32ES007324 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CUDDAPAH, SURESH · 1999 to 2025
$5.8M
NIEHS NIH HHS ES000260NIEHS NIH HHS ES007324NIEHS NIH HHS P30 ES000260NIEHS NIH HHS T32 ES007324
6 · The paper itself

Abstract

backgroundPrevious human exposure studies of traffic-related air pollutants have demonstrated adverse health effects in human populations by comparing areas of high and low traffic, but few studies have utilized microenvironmental monitoring of pollutants at multiple traffic locations while looking at a vast array of health endpoints in the same population. We evaluated inflammatory markers, heart rate variability (HRV), blood pressure, exhaled nitric oxide, and lung function in healthy participants after exposures to varying mixtures of traffic pollutants.

methodsA repeated-measures, crossover study design was used in which 23 healthy, non-smoking adults had clinical cardiopulmonary and systemic inflammatory measurements taken prior to, immediately after, and 24 hours after intermittent walking for two hours in the summer months along three diverse roadways having unique emission characteristics. Measurements of PM2.5, PM10, black carbon (BC), elemental carbon (EC), and organic carbon (OC) were collected. Mixed effect models were used to assess changes in health effects associated with these specific pollutant classes.

resultsMinimal associations were observed with lung function measurements and the pollutants measured. Small decreases in BP measurements and rMSSD, and increases in IL-1β and the low frequency to high frequency ratio measured in HRV, were observed with increasing concentrations of PM2.5 EC.

conclusionsSmall, acute changes in cardiovascular and inflammation-related effects of microenvironmental exposures to traffic-related air pollution were observed in a group of healthy young adults. The associations were most profound with the diesel-source EC.

Indexed as

Environmental ExposureAdolescentAdultAir PollutantsBlood PressureCross-Over StudiesFemaleHeart RateHumansInflammationMaleNew JerseyNew YorkParticulate MatterVehicle EmissionsYoung AdultAir PollutantsParticulate MatterVehicle Emissions

Identifiers

PMID26276052
PMCPMC4537534
OpenAlexW2140803234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.