Evidence map›Paper›PMID 26275784›Full record

ReviewCurrent oncology reports2015

Integrating Immunotherapies in Prostate Cancer.

Julius Strauss, Ravi A Madan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Epidemiology, Staging and Management of Prostate Cancer.Medical sciences (Basel, Switzerland) · 2020
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Julius StraussGenitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, 9000 Rockville Pike, Bldg 10/ Room 12 N-226, Bethesda, MD, 20892, USA, julius.strauss@nih.gov.
Ravi A Madan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, immunotherapy has emerged as a viable and promising treatment for prostate cancer. Beyond sipulecuel-T, phase III trials are evaluating multiple vaccine and immune-based therapies in men with this disease. Evidence suggests that many of these therapies are effective at augmenting immune responses and slowing tumor growth rates. Yet prospective data evaluating these responses as surrogates for survival are still needed. In the absence of validated intermediate markers of response, growing data suggests that patients with more indolent disease are more likely to benefit from immunotherapies. In order to further optimize immunotherapy use, ongoing trials are evaluating its combination with traditional as well as other immune-based treatments. Preliminary data from these trials are promising and are shedding new light on this area.

Indexed as

Antigens, CDCancer VaccinesClinical Trials, Phase III as TopicCombined Modality TherapyHumansImmunization, PassiveImmunotherapyMaleProstate-Specific AntigenProstatic NeoplasmsAntigens, CDCancer VaccinesProstate-Specific Antigen

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.