Evidence map›Paper›PMID 26275453›Full record

Trial reportInternational journal of epidemiology2015

Effect of fortified complementary food supplementation on child growth in rural Bangladesh: a cluster-randomized trial.

Parul Christian, Saijuddin Shaikh, Abu Ahmed Shamim, Sucheta Mehra, Lee Wu, Maithilee Mitra, Hasmot Ali, Rebecca D Merrill, Nuzhat Choudhury, Monira Parveen and 9 more

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 15 pooled it
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 15 syntheses or guidelines pooled it, 6 citations in OpenAlex.

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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 3 countries.

Parul ChristianDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA, pchrist1@jhu.edu.
Saijuddin ShaikhDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA, JiVitA Project, Gaibandha, Bangladesh.
Abu Ahmed ShamimJiVitA Project, Gaibandha, Bangladesh.
Sucheta MehraDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Lee WuDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Maithilee MitraDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Hasmot AliDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA, JiVitA Project, Gaibandha, Bangladesh.
Rebecca D MerrillDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Nuzhat ChoudhuryCentre for Nutrition and Food Security, International Centre for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka, Bangladesh.
Monira ParveenUnited Nations World Food Programme, IDB Bhaban, Dhaka, Bangladesh and.
Rachel D FuliUnited Nations World Food Programme, IDB Bhaban, Dhaka, Bangladesh and.
Md Iqbal HossainCentre for Nutrition and Food Security, International Centre for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka, Bangladesh.
Md Munirul IslamCentre for Nutrition and Food Security, International Centre for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka, Bangladesh.
Rolf KlemmDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Kerry SchulzeDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Alain LabriqueDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Saskia de PeeOffice of Nutrition Advisor, United Nations World Food Programme, Rome, Italy.
Tahmeed AhmedCentre for Nutrition and Food Security, International Centre for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka, Bangladesh.
Keith P WestDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Johns Hopkins University · USInternational Centre for Diarrhoeal Disease Research · BDWorld Food Programme · ITWorld University of Bangladesh · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGrowth faltering in the first 2 years of life is high in South Asia where prevalence of stunting is estimated at 40-50%. Although nutrition counselling has shown modest benefits, few intervention trials of food supplementation exist showing improvements in growth and prevention of stunting.

methodsA cluster-randomized controlled trial was conducted in rural Bangladesh to test the effect of two local, ready-to-use foods (chickpea and rice-lentil based) and a fortified blended food (wheat-soy-blend++, WSB++) compared with Plumpy'doz, all with nutrition counselling vs nutrition counselling alone (control) on outcomes of linear growth (length and length-for-age z-score, LAZ), stunting (LAZ < -2), weight-for-length z-score (WLZ) and wasting (WLZ < -2) in children 6-18 months of age. Children (n = 5536) were enrolled at 6 months of age and, in the food groups, provided with one of the allocated supplements daily for a year.

resultsGrowth deceleration occurred from 6 to 18 months of age but deceleration in LAZ was lower (by 0.02-0.04/month) in the Plumpy'doz (P = 0.02), rice-lentil (< 0.01), and chickpea (< 0.01) groups relative to control, whereas WLZ decline was lower only in Plumpy'doz and chickpea groups. WSB++ did not impact on these outcomes. The prevalence of stunting was 44% at 18 months in the control group, but lower by 5-6% (P ≤ 0.01) in those receiving Plumpy'doz and chickpea. Mean length and LAZ at 18 months were higher by 0.27-0.30 cm and 0.07-0.10 (all P < 0.05), respectively, in all four food groups relative to the control.

conclusionsIn rural Bangladesh, small amounts of daily fortified complementary foods, provided for a year in addition to nutrition counselling, modestly increased linear growth and reduced stunting at 18 months of age.

Indexed as

Breast FeedingDietary SupplementsFood, FortifiedRural PopulationBangladeshChild DevelopmentCicerCounselingDietary SucroseFemaleGrowth DisordersHumansInfantInfant Nutrition DisordersLens PlantMaleDietary SucroseMicronutrientsSoybean OilBangladeshComplementary foodgrowthmicronutrientsstuntingsupplementation

Identifiers

PMID26275453
PMCPMC4689999
OpenAlexW1566714310

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.