Evidence map›Paper›PMID 26274916›Full record

ArticlePLoS neglected tropical diseases2015

Risk Factors for Death from Visceral Leishmaniasis in an Urban Area of Brazil.

Angelita F Druzian, Albert S de Souza, Diogo N de Campos, Julio Croda, Minoru G Higa, Maria Elizabeth C Dorval, Mauricio A Pompilio, Polliana A de Oliveira, Anamaria M M Paniago

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

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  12. A Computational Approach Using Bioinformatics to Screening Drug Targets forEvidence-based complementary and alternative medicine : eCAM · 2018
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  13. Human Competence to TransmitThe American journal of tropical medicine and hygiene · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Angelita F DruzianUniversity Hospital, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil; Post Graduation Program in Infectious and Parasitic Diseases, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Albert S de SouzaCenter for Biological and Health Sciences, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Diogo N de CamposMedicine Faculty, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Julio CrodaOswaldo Cruz Foundation-Fiocruz, Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil; Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil.
Minoru G HigaPost Graduation Program in Infectious and Parasitic Diseases, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Maria Elizabeth C DorvalPost Graduation Program in Infectious and Parasitic Diseases, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil; Center for Biological and Health Sciences, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Mauricio A PompilioMedicine Faculty, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Polliana A de OliveiraMedicine Faculty, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Anamaria M M PaniagoPost Graduation Program in Infectious and Parasitic Diseases, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil; Medicine Faculty, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Universidade Federal de Mato Grosso do Sul · BRFundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOver the last three decades, the epidemiological profile of visceral leishmaniasis (VL) has changed with epidemics occurring in large urban centers of Brazil, an increase in HIV/AIDS co-infection, and a significant increase in mortality. The objective of this study was to identify the risk factors associated with death among adult patients with VL from an urban endemic area of Brazil. METHODOLOGY: A prospective cohort study included 134 adult patients with VL admitted to the University Hospital of the Federal University of Mato Grosso do Sul between August 2011 and August 2013. PRINCIPAL

findingsPatients ranged from 18 to 93 years old, with a mean age of 43.6 (±15.7%). Of these patients, 36.6% were co-infected with HIV/AIDS, and the mortality rate was 21.6%. In a multivariate analysis, the risk factors associated with death were secondary bacterial infection (42.86, 5.05-363.85), relapse (12.17, 2.06-71.99), edema (7.74, 1.33-45.05) and HIV/AIDS co-infection (7.33, 1.22-43.98). CONCLUSIONS/SIGNIFICANCE: VL has a high mortality rate in adults from endemic urban areas, especially when coinciding with high rates of HIV/AIDS co-infection.

Indexed as

Urban PopulationAdolescentAdultAgedAged, 80 and overBrazilCohort StudiesFemaleHumansLeishmaniasis, VisceralMaleMiddle AgedRisk FactorsYoung Adult

Identifiers

PMID26274916
PMCPMC4537269
OpenAlexW1195121442

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.