Evidence map›Paper›PMID 26274754›Full record

ArticleAnnals of the Royal College of Surgeons of England2015

A prospective cohort study of risk prediction in simultaneous pancreas and kidney transplantation.

H A Khambalia, Z Moinuddin, A M Summers, A Tavakoli, R Pararajasingam, T Campbell, R Dhanda, B Forgacs, T Augustine, D van Dellen

Registry-linked trialAbstract read
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In one paragraph

Article in Annals of the Royal College of Surgeons of England, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03933137 (Correlation Between P-POSSUM Score and Length of Stay in Kidney Transplant Recipients), which is not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03933137 completednot on this mapstarted 2018, after this paper: background citation

Correlation Between P-POSSUM Score and Length of Stay in Kidney Transplant Recipients

TypeobservationalSponsorIndonesia UniversityRan2018 to 2018Enrolled225ConditionsLength of StayArmsPortsmouth Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (P-POSSUM) score
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Waterlow score for risk assessment in surgical patients: a systematic review.Annals of the Royal College of Surgeons of England · 2021
    Pooled it
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

H A KhambaliaCentral Manchester University Hospitals NHS Foundation Trust , UK.
Z MoinuddinCentral Manchester University Hospitals NHS Foundation Trust , UK.
A M SummersCentral Manchester University Hospitals NHS Foundation Trust , UK.
A TavakoliCentral Manchester University Hospitals NHS Foundation Trust , UK.
R PararajasingamCentral Manchester University Hospitals NHS Foundation Trust , UK.
T CampbellCentral Manchester University Hospitals NHS Foundation Trust , UK.
R DhandaCentral Manchester University Hospitals NHS Foundation Trust , UK.
B ForgacsCentral Manchester University Hospitals NHS Foundation Trust , UK.
T AugustineCentral Manchester University Hospitals NHS Foundation Trust , UK.
D van DellenCentral Manchester University Hospitals NHS Foundation Trust , UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCurrent risk prediction scoring systems in pancreas transplantation are limited to organ factors and are specific to predicting graft outcome. They do not consider recipient factors or inform regarding recipient morbidity. The aim of this study was to assess the utility of commonly used general surgical risk prediction models (P-POSSUM [Portsmouth Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity], MODS [multiple organ dysfunction score], Charlson co-morbidity index, revised cardiac risk index, ASA [American Society of Anesthesiologists] grade and Waterlow score), and to correlate them with total length of hospital stay (LOS) and critical care unit (CCU) LOS, important surrogate markers of patient outcome.

methodsAll risk prediction scores were calculated prospectively for all simultaneous pancreas and kidney (SPK) transplant recipients from November 2011 to October 2013, and correlated with outcome measures.

resultsOverall, 57 SPK transplant recipients were analysed. The mean age was 42.0 years (standard deviation [SD]: 7.60 years), 27 (52%) were male and the mean body mass index was 25.43kg/m(2) (SD: 3.11kg/m(2)). The mean pancreas and kidney cold ischaemic times were 703 minutes (SD: 182 minutes) and 850 minutes (SD: 192 minutes) respectively. The median total LOS and mean CCU LOS was 17 days (range: 8-79 days) and 7 days (SD: 4.04 days) respectively. When correlated with risk prediction scores, Waterlow score was the only significant predictor of total LOS and CCU LOS (p<0.001 [Spearman's correlation] and p=0.001 [Pearson's correlation] respectively).

conclusionsPreoperative risk prediction plays an important part in planning perioperative care. To date, no validated risk prediction scoring system exists for SPK transplantation. This prospective study indicates that Waterlow score identifies high risk individuals and has value in the prediction of outcome following SPK transplantation.

Indexed as

AdultCohort StudiesFemaleHumansKidney TransplantationLength of StayMaleMiddle AgedPancreas TransplantationProspective StudiesRisk AssessmentSeverity of Illness IndexTissue DonorsTreatment OutcomeYoung AdultOutcome assessmentPancreas transplantationRisk

Identifiers

PMID26274754
PMCPMC5126239

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