ReviewJournal of neurosurgical anesthesiology2016
The Neurobiology of Anesthetic Emergence.
Review in Journal of neurosurgical anesthesiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Early reactivation of medial temporal lobe neurons during emergence from propofol anesthesia in neurosurgical patients.bioRxiv : the preprint server for biology · 2026Article
- Subcortical recruitment dissociates isoflurane emergence from distinct wakeful states in mice.bioRxiv : the preprint server for biology · 2026Article
- Zona Incerta GABAergic Neurons Facilitate Emergence from Isoflurane Anesthesia in Mice.Neurochemical research · 2024Article
- Activation of Ventral Tegmental Area Dopaminergic Neurons Projecting to the Parabrachial Nucleus Promotes Emergence from Propofol Anesthesia in Male Rats.Neurochemical research · 2024Article
- Time to Wake Up! The Ongoing Search for General Anesthetic Reversal Agents.Anesthesiology · 2024Article
- Emergence Patterns from General Anesthesia after Epilepsy Surgery: An Observational Pilot Study.Asian journal of neurosurgery · 2023Article
- [Disorders of consciousness after general anesthesia].Die Anaesthesiologie · 2023Article
- Use of Ketamine or Xylazine to Provide Balanced Anesthesia with Isoflurane in C57BL/6J Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022Article
- Historical and Modern Evidence for the Role of Reward Circuitry in Emergence.Anesthesiology · 2022Review
- Identifying c-fos Expression as a Strategy to Investigate the Actions of General Anesthetics on the Central Nervous System.Current neuropharmacology · 2022Review
- Article
- Sevoflurane and Desflurane Exposures Following Aneurysmal Subarachnoid Hemorrhage Confer Multifaceted Protection against Delayed Cerebral Ischemia.Biomedicines · 2021Article
- Effects of Oxygen Supplementation on Injectable and Inhalant Anesthesia in C57BL/6 Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2021Article
- Inactivation of Prefrontal Cortex Delays Emergence From Sevoflurane Anesthesia.Frontiers in systems neuroscience · 2021Article
- Locus Coeruleus to Paraventricular Thalamus Projections Facilitate Emergence From Isoflurane Anesthesia in Mice.Frontiers in pharmacology · 2021Article
- Effects of Standard and Sustained-release Buprenorphine on the Minimum Alveolar Concentration of Isoflurane in C57BL/6 Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2020Article
- Delayed Emergence from Anesthesia: What We Know and How We Act.Local and regional anesthesia · 2020Review
- Escape From Oblivion: Neural Mechanisms of Emergence From General Anesthesia.Anesthesia and analgesia · 2019Review
- Nonlinear dynamics captures brain states at different levels of consciousness in patients anesthetized with propofol.PloS one · 2019Article
- Towards a better understanding of anesthesia emergence mechanisms: Research and clinical implications.World journal of methodology · 2018Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Achieving a smooth and rapid emergence from general anesthesia is of particular importance for neurosurgical patients and is a clinical goal for neuroanesthesiologists. Recent data suggest that the process of emergence is not simply the mirror image of induction, but rather controlled by distinct neural circuits. In this narrative review, we discuss (1) hysteresis, (2) the concept of neural inertia, (3) the asymmetry between the neurobiology of induction and emergence, and (4) recent attempts at actively inducing emergence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.