ArticleJournal of diabetes research2015
Inflammatory Cytokine Profile Associated with Metabolic Syndrome in Adult Patients with Type 1 Diabetes.
Article in Journal of diabetes research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 28 citations in OpenAlex.
- Article
- The Influence of Sociodemographic Characteristics, Lifestyle, and Metabolic Syndrome on Anxiety and Depression Symptoms in Adults in Banja Luka.Acta medica academica · 2025Article
- The effect of physical activity on cytokine levels in adults living with type 1 diabetes-a preliminary study.Physiological reports · 2024Article
- Metabolic syndrome and associated factors amongFrontiers in endocrinology · 2024Article
- B-Cell Activating Factor Increases Related to Adiposity, Insulin Resistance, and Endothelial Dysfunction in Overweight and Obese Subjects.Life (Basel, Switzerland) · 2022Article
- Serum adipokine levels in patients with type 1 diabetes are associated with degree of obesity but only resistin is independently associated with atherosclerosis markers.Hormones (Athens, Greece) · 2022Article
- Global prevalence of metabolic syndrome among patients with type I diabetes mellitus: a systematic review and meta-analysis.Diabetology & metabolic syndrome · 2021Review
- Comparison of indirect markers of insulin resistance in adult patients with Double Diabetes.BMC endocrine disorders · 2020Article
- IL-6 and type 1 diabetes mellitus: T cell responses and increase in IL-6 receptor surface expression.Annals of translational medicine · 2017Article
- Adipokines, diabetes and atherosclerosis: an inflammatory association.Frontiers in physiology · 2015Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the serum concentration of IL-6, IL-10, TNF, IL-8, resistin, and adiponectin in type 1 diabetic patients with and without metabolic syndrome and to determine the cut-off point of the estimated glucose disposal rate that accurately differentiated these groups.
designWe conducted a cross-sectional evaluation of all patients in our type 1 diabetes clinic from January 2012 to January 2013. Patients were considered to have metabolic syndrome when they fulfilled the joint statement criteria and were evaluated for clinical, biochemical, and immunological features.
methodsWe determined serum IL-6, IL-8, IL-10, and TNF with flow cytometry and adiponectin and resistin concentrations with enzyme linked immunosorbent assay in patients with and without metabolic syndrome. We also compared estimated glucose disposal rate between groups.
resultsWe tested 140 patients. Forty-four percent fulfilled the metabolic syndrome criteria (n = 61), 54% had central obesity, 30% had hypertriglyceridemia, 29% had hypoalphalipoproteinemia, and 19% had hypertension. We observed that resistin concentrations were higher in patients with MS.
conclusion. We found a high prevalence of MS in Mexican patients with T1D. The increased level of resistin may be related to the increased fat mass and could be involved in the development of insulin resistance.
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