Evidence map›Paper›PMID 26273645›Full record

ArticleBioMed research international2015

Prediction of MicroRNA-Disease Associations Based on Social Network Analysis Methods.

Quan Zou, Jinjin Li, Qingqi Hong, Ziyu Lin, Yun Wu, Hua Shi, Ying Ju

Abstract read
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed.

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  16. Graph regularized LBMC bioinformatics · 2020
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  20. 6mA-RicePred: A Method for Identifying DNAFrontiers in plant science · 2020
    Article

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Quan ZouSchool of Information Science and Technology, Xiamen University, Xiamen 361005, China ; School of Computer Science and Technology, Tianjin University, Tianjin 300072, China.
Jinjin LiSchool of Information Science and Technology, Xiamen University, Xiamen 361005, China.
Qingqi HongSoftware School, Xiamen University, Xiamen 361005, China.
Ziyu LinSchool of Information Science and Technology, Xiamen University, Xiamen 361005, China.
Yun WuCollege of Computer and Information Engineering, Xiamen University of Technology, Xiamen 361024, China.
Hua ShiCollege of Computer and Information Engineering, Xiamen University of Technology, Xiamen 361024, China.
Ying JuSchool of Information Science and Technology, Xiamen University, Xiamen 361005, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs constitute an important class of noncoding, single-stranded, ~22 nucleotide long RNA molecules encoded by endogenous genes. They play an important role in regulating gene transcription and the regulation of normal development. MicroRNAs can be associated with disease; however, only a few microRNA-disease associations have been confirmed by traditional experimental approaches. We introduce two methods to predict microRNA-disease association. The first method, KATZ, focuses on integrating the social network analysis method with machine learning and is based on networks derived from known microRNA-disease associations, disease-disease associations, and microRNA-microRNA associations. The other method, CATAPULT, is a supervised machine learning method. We applied the two methods to 242 known microRNA-disease associations and evaluated their performance using leave-one-out cross-validation and 3-fold cross-validation. Experiments proved that our methods outperformed the state-of-the-art methods.

Indexed as

Databases, GeneticMachine LearningModels, GeneticAlgorithmsComputer SimulationGenetic Predisposition to DiseaseHumansMicroRNAsPattern Recognition, AutomatedSignal TransductionSocial NetworkingMicroRNAs

Identifiers

PMID26273645
PMCPMC4529919

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.