Evidence map›Paper›PMID 26273589›Full record

ArticleBioMed research international2015

Histological and Histomorphometric Human Results of HA-Beta-TCP 30/70 Compared to Three Different Biomaterials in Maxillary Sinus Augmentation at 6 Months: A Preliminary Report.

Susanna Annibali, Giovanna Iezzi, Gian Luca Sfasciotti, Maria Paola Cristalli, Iole Vozza, Carlo Mangano, Gerardo La Monaca, Antonella Polimeni

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PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Susanna AnnibaliDepartment of Oral and Maxillofacial Sciences, Oral Surgery Unit, School of Dentistry, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.
Giovanna IezziDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy.
Gian Luca SfasciottiDepartment of Oral and Maxillofacial Sciences, Oral Surgery Unit, School of Dentistry, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.
Maria Paola CristalliDepartment of Biotechnologies and Medical Surgical Sciences, Sapienza University of Rome, Rome, Italy.
Iole VozzaDepartment of Oral and Maxillofacial Sciences, Oral Surgery Unit, School of Dentistry, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.
Carlo ManganoDepartment of Surgical and Morphological Sciences, University of Insubria, Varese, Italy.
Gerardo La MonacaDepartment of Oral and Maxillofacial Sciences, Oral Surgery Unit, School of Dentistry, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.
Antonella PolimeniDepartment of Oral and Maxillofacial Sciences, Oral Surgery Unit, School of Dentistry, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this investigation was to examine the bone regenerative potential of newly biphasic calcium phosphate ceramics (HA-β-TCP 30/70), by assessing histological and histomorphometric results of human specimens retrieved from sinuses augmented with HA-β-TCP 30/70, and comparing them to anorganic bovine bone (ABB), mineralized solvent-dehydrated bone allograft (MSDBA), and equine bone (EB), after a healing period of 6 months. MATERIALS AND

methodsFour consecutive patients with edentulous atrophic posterior maxilla were included in this report. A two-stage procedure was carried out for sinus augmentation with HA-β-TCP 30/70, ABB, MSDBA, and EB. After 6 months, specimens were retrieved at the time of implant placement and processed for histological and histomorphometric analyses.

resultsAt histological examination, all biomaterials were in close contact with the newly formed bone and showed the same pattern of bone formation; the grafted granules were surrounded by a bridge-like network of newly formed bone. A limited number of ABB particles were partially covered by connective tissue. The histomorphometric analysis revealed 30.2% newly formed bone for Ha-β-TCP 30/70, 20.1% for ABB, 16.4% for MSDBA, and 21.9% for EB.

conclusionsWithin the limitations of the present investigation, these results support the successful use of HA-β-TCP 30/70 for sinus augmentation.

Indexed as

AdultAgedBone SubstitutesBone TransplantationCalcium PhosphatesDurapatiteFemaleHumansMaleMaxillary SinusMiddle AgedPilot ProjectsSinus Floor AugmentationTreatment OutcomeBone SubstitutesCalcium PhosphatesDurapatitetricalcium phosphate

Identifiers

PMID26273589
PMCPMC4529888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.