ReviewClinical and experimental vaccine research2015
Safety of influenza vaccination in children with allergic diseases.
Review in Clinical and experimental vaccine research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- Mendelian randomization analysis reveals causal relationship between allergic diseases and influenza.The World Allergy Organization journal · 2025Article
- Allergic Reactions to Vaccines in Children: From Constituents to Specific Vaccines.Biomedicines · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Global guidelines strongly recommend annual influenza vaccination in people age 6 months and older, particularly in asthmatic children. There is no doubt about the benefit of influenza vaccination in asthmatic children. However, some of the vaccine's components may elicit an IgE mediated hypersensitivity or disease exacerbation, including life-threatening events, in children with allergic diseases. As a result, concerns regarding the safety of the vaccine still continue today. The influenza vaccine is grown on hens' eggs and contains a trace of egg protein. Consequently, it can provoke an allergic reaction or anaphylaxis in children with an egg allergy or exacerbation in those with asthma. Therefore, we need to know the risks and benefits of the influenza vaccine and the best strategy for safe vaccination. Although most guidelines have consistently reported the safety of influenza vaccination in children with allergic disease, and have recommended annual administration, safety concerns impede guideline-based performance in practice. The safety and efficacy of influenza vaccination for allergic children are summarized in the present review.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.