Evidence map›Paper›PMID 26273525›Full record

ArticleBone research2014

Bone density, microarchitecture and stiffness in Caucasian and Caribbean Hispanic postmenopausal American women.

Bin Zhou, Ji Wang, Emily M Stein, Zhendong Zhang, Kyle K Nishiyama, Chiyuan A Zhang, Thomas L Nickolas, Elizabeth Shane, X Edward Guo

Open access · goldAbstract read
In one paragraph

Article in Bone research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Transversal changes, space closure, and efficiency of conventional and self-ligating appliances : A quantitative systematic review.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2018
    Pooled it
  2. Article
  3. Article
  4. Racial and Ethnic Disparities in Bone Health and Outcomes in the United States.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021
    Review
  5. Article
  6. Article
  7. Article
  8. Association of trabecular bone score (TBS) and prior fracture differs among minorities in NHANES 2005-2008.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Article
  9. Prevalence of Osteoporosis and Low Bone Mass Among Puerto Rican Older Adults.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2018
    Article
  10. Characterization of trabecular bone microstructure in premenopausal women with distal radius fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Article
  11. Cortical microstructure compensates for smaller bone size in young Caribbean Hispanic versus non-Hispanic white men.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Article
  12. Pattern recognition letters · 2016
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Bin ZhouBone Bioengineering Laboratory, Department of Biomedical Engineering, Columbia University , New York, USA.
Ji WangBone Bioengineering Laboratory, Department of Biomedical Engineering, Columbia University , New York, USA.
Emily M SteinDivision of Endocrinology, Department of Medicine, Columbia University , New York, USA.
Zhendong ZhangBone Bioengineering Laboratory, Department of Biomedical Engineering, Columbia University , New York, USA ; Department of Orthopedic Surgery, First Affiliated Hospital, School of Medicine Shihezi University , Shihezi, Xinjiang, China.
Kyle K NishiyamaDivision of Endocrinology, Department of Medicine, Columbia University , New York, USA.
Chiyuan A ZhangDivision of Endocrinology, Department of Medicine, Columbia University , New York, USA.
Thomas L NickolasDivision of Endocrinology, Department of Medicine, Columbia University , New York, USA.
Elizabeth ShaneDivision of Endocrinology, Department of Medicine, Columbia University , New York, USA.
X Edward GuoBone Bioengineering Laboratory, Department of Biomedical Engineering, Columbia University , New York, USA.
Columbia University · USShihezi University · CN

Funding

Micro-Mechanical Modeling of Trabecular BoneR01AR051376 · NIAMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GUO, X. EDWARD · 2006 to 2015
$3.2M
Clinical Bone Mechanics Using HR-pQCT and ??MRIR01AR058004 · NIAMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GUO, X. EDWARD, SHANE, ELIZABETH J · 2010 to 2014
$3.1M
NIAMS NIH HHS R01 AR051376NIAMS NIH HHS R01 AR058004
6 · The paper itself

Abstract

Hispanic Americans of Caribbean origin are a fast-growing subset of the US population, but there are no studies on bone density, microstructure and biomechanical integrity in this minority group. In this study, we aimed to compare Caucasian and Caribbean Hispanic postmenopausal American women with respect to these characteristics. Thirty-three Caribbean Hispanics were age-matched to thirty-three Caucasian postmenopausal women. At the lumbar spine, the Hispanic women had significantly lower areal bone mineral density (aBMD). At the radius by high-resolution peripheral quantitative computed tomography (HR-pQCT), there were minimal differences between Hispanic and Caucasian women. At the tibia, Hispanic women had lower trabecular volumetric bone density and trabecular number, and higher trabecular separation. Individual trabecula segmentation (ITS) analyses indicated that at the tibia, Hispanic women not only had significantly lower bone volume fraction, but also had significantly lower rod bone volume fraction, plate trabecular number, rod trabecular number and lower plate-plate, plate-rod and rod-rod junction densities compared to Caucasian women. The differences in bone quantity and quality contributed to lower whole bone stiffness at the radius, and both whole bone and trabecular bone stiffness at the tibia in Hispanic women. In conclusion, Hispanic women had poorer bone mechanical and microarchitectural properties than Caucasian women, especially at the load-bearing distal tibia.

Identifiers

PMID26273525
PMCPMC4472134
OpenAlexW112358453

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.