Evidence map›Paper›PMID 26273379›Full record

ArticleThoracic cancer2015

Percutaneous radiofrequency ablation for medically inoperable patients with clinical stage I non-small cell lung cancer.

Baodong Liu, Lei Liu, Mu Hu, Kun Qian, Yuanbo Li

Abstract read
In one paragraph

Article in Thoracic cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Radiofrequency ablationJournal of Cancer · 2021
    Article
  8. Review
  9. [Advances and Challenges of Local Thermal Ablation in Non-small Cell Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2020
    Review
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Baodong LiuDepartment of Thoracic Surgery, Xuanwu Hospital of Capital Medical University Beijing, China.
Lei LiuDepartment of Thoracic Surgery, Xuanwu Hospital of Capital Medical University Beijing, China.
Mu HuDepartment of Thoracic Surgery, Xuanwu Hospital of Capital Medical University Beijing, China.
Kun QianDepartment of Thoracic Surgery, Xuanwu Hospital of Capital Medical University Beijing, China.
Yuanbo LiDepartment of Thoracic Surgery, Xuanwu Hospital of Capital Medical University Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA retrospective evaluation of percutaneous radiofrequency ablation (RFA) in medically inoperable patients with clinical stage I non-small cell lung cancer (NSCLC).

methodsBetween 2008 and 2014, 29 medically inoperable patients with clinical stage I NSCLC underwent percutaneous RFA. We evaluated the feasibility, safety, and effectiveness.

resultsThere were 18 men and 11 women with a median age of 78.0 years (range 56-85), mean 76.0 years. No procedure-related deaths occurred in any of the 33 ablation procedures. The mean follow-up was 25 months. The incidence of local tumor progression was 21.0% at 25 months of median time to progression after the initial RFA. The mean overall survival (OS) was 57 months (95% confidence interval (CI) 44-70 months). The mean cancer-specific survival CSS was 63 months (95% CI 50-75 months). OS was 90.5% ± 6.4% at one year, 76.4% ± 10.7% at two, and 65.5% ± 13.6% at three years. CSS was 95.2% ± 4.6% at one, 86.6% ± 9.3% at two, and 74.2% ± 13.9% at three years in all patients. The survival for stage IA and IB cancers were 87.5% and 92.3% at one, 87.5% and 73.4% at two, and 87.5% and 58.7% at three years, respectively. Survival rates were not significantly different between the two groups (P = 0.596), with mean survival times of 65 (95% CI: 51-79 months) and 55 months (95% CI: 38-71 months), respectively.

conclusionPercutaneous RFA is a safe, feasible, and effective procedure in medically inoperable clinical stage I NSCLC patients.

Indexed as

Computed tomographynon-small cell lung cancerradiofrequency ablation

Identifiers

PMID26273379
PMCPMC4448392

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.