Evidence map›Paper›PMID 26273274›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2015

Molecular typing of Argentinian Mycobacterium avium subsp. paratuberculosis isolates by multiple-locus variable number-tandem repeat analysis.

Andrea Gioffré, Magnolia Correa Muñoz, María F Alvarado Pinedo, Roberto Vaca, Claudia Morsella, María Andrea Fiorentino, Fernando Paolicchi, Paula Ruybal, Martín Zumárraga, Gabriel E Travería and 1 more

Abstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Paratuberculosis in Latin America: a systematic review.Tropical animal health and production · 2017
    Pooled it
  4. East AsianJournal of veterinary science · 2026
    Article
  5. Evidence ofJournal of veterinary science · 2025
    Article
  6. Article
  7. High Molecular Diversity ofInternational journal of molecular sciences · 2025
    Article
  8. Article
  9. Article
  10. Molecular Diversity ofAnimals : an open access journal from MDPI · 2023
    Article
  11. Article
  12. Article
  13. Genotyping methods and molecular epidemiology ofInternational journal of veterinary science and medicine · 2018
    Review
  14. Genetic diversity of bovineJournal of veterinary science · 2018
    Article
  15. Article
  16. Nontuberculous mycobacteria in patients with suspected tuberculosis and the genetic diversity of Mycobacterium avium in the extreme south of Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andrea GioffréInstituto Nacional de Tecnología Agropecuaria, Instituto de Biotecnología, Centro de Investigación en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria, Buenos Aires, Argentina, Instituto de Biotecnología, Centro de Investigación en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria, Buenos Aires, Argentina.
Magnolia Correa MuñozUniversidad Autónoma de Baja California, Universidad Autónoma de Baja California, Mexicali, México, Universidad Autónoma de Baja California, Mexicali, México.
María F Alvarado PinedoUniversidad Nacional de La Plata, Centro de Diagnóstico e Investigaciones Veterinarias, Faculdad de Ciencias Veterinarias, Universidad Nacional de La Plata, Chascomús, Argentina, Centro de Diagnóstico e Investigaciones Veterinarias, Faculdad de Ciencias Veterinarias, Universidad Nacional de La Plata, Chascomús, Argentina.
Roberto VacaUniversidad Nacional de La Plata, Cátedra de Zootecnia Especial II, Faculdad de Ciencias Veterinarias, Universidad Nacional de La Plata, Buenos Aires, Argentina, Cátedra de Zootecnia Especial II, Faculdad de Ciencias Veterinarias, Universidad Nacional de La Plata, Buenos Aires, Argentina.
Claudia MorsellaInstituto Nacional de Tecnología Agropecuaria, Laboratorio de Bacteriología, Estación Experimental Agropecuaria, Instituto Nacional de Tecnología Agropecuaria, Balcarce, Argentina, Laboratorio de Bacteriología, Estación Experimental Agropecuaria, Instituto Nacional de Tecnología Agropecuaria, Balcarce, Argentina.
María Andrea FiorentinoInstituto Nacional de Tecnología Agropecuaria, Laboratorio de Bacteriología, Estación Experimental Agropecuaria, Instituto Nacional de Tecnología Agropecuaria, Balcarce, Argentina, Laboratorio de Bacteriología, Estación Experimental Agropecuaria, Instituto Nacional de Tecnología Agropecuaria, Balcarce, Argentina.
Fernando PaolicchiInstituto Nacional de Tecnología Agropecuaria, Laboratorio de Bacteriología, Estación Experimental Agropecuaria, Instituto Nacional de Tecnología Agropecuaria, Balcarce, Argentina, Laboratorio de Bacteriología, Estación Experimental Agropecuaria, Instituto Nacional de Tecnología Agropecuaria, Balcarce, Argentina.
Paula RuybalInstituto Nacional de Tecnología Agropecuaria, Instituto de Biotecnología, Centro de Investigación en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria, Buenos Aires, Argentina, Instituto de Biotecnología, Centro de Investigación en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria, Buenos Aires, Argentina.
Martín ZumárragaInstituto Nacional de Tecnología Agropecuaria, Instituto de Biotecnología, Centro de Investigación en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria, Buenos Aires, Argentina, Instituto de Biotecnología, Centro de Investigación en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria, Buenos Aires, Argentina.
Gabriel E TraveríaUniversidad Nacional de La Plata, Centro de Diagnóstico e Investigaciones Veterinarias, Faculdad de Ciencias Veterinarias, Universidad Nacional de La Plata, Chascomús, Argentina, Centro de Diagnóstico e Investigaciones Veterinarias, Faculdad de Ciencias Veterinarias, Universidad Nacional de La Plata, Chascomús, Argentina.
María Isabel RomanoInstituto Nacional de Tecnología Agropecuaria, Instituto de Biotecnología, Centro de Investigación en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria, Buenos Aires, Argentina, Instituto de Biotecnología, Centro de Investigación en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria, Buenos Aires, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple-locus variable number-tandem repeat analysis (MLVA) of Mycobacterium avium subspecies paratuberculosis (MAP) isolates may contribute to the knowledge of strain diversity in Argentina. Although the diversity of MAP has been previously investigated in Argentina using IS900-RFLP, a small number of isolates were employed, and a low discriminative power was reached. The aim of the present study was to test the genetic diversity among MAP isolates using an MLVA approach based on 8 repetitive loci. We studied 97 isolates from cattle, goat and sheep and could describe 7 different patterns: INMV1, INMV2, INMV11, INMV13, INMV16, INMV33 and one incomplete pattern. INMV1 and INMV2 were the most frequent patterns, grouping 76.3% of the isolates. We were also able to demonstrate the coexistence of genotypes in herds and co-infection at the organism level. This study shows that all the patterns described are common to those described in Europe, suggesting an epidemiological link between the continents.

Indexed as

Genetic VariationMinisatellite RepeatsAnimalsArgentinaCattleCattle DiseasesGenotypeGoat DiseasesGoatsMolecular EpidemiologyMolecular TypingMycobacterium avium subsp. paratuberculosisParatuberculosisSheepSheep DiseasesMIRU-VNTRMLVAmolecular typingparatuberculosis

Identifiers

PMID26273274
PMCPMC4507551

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.