Evidence map›Paper›PMID 26273262›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2015

Nosocomial candidiasis in Rio de Janeiro State: Distribution and fluconazole susceptibility profile.

Paulo Murillo Neufeld, Marcia de Souza Carvalho Melhem, Maria Walderez Szeszs, Marcos Dornelas Ribeiro, Efigênia de Lourdes Teixeira Amorim, Manuela da Silva, Marcia dos Santos Lazéra

Abstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Meyerozyma guilliermondii species complex: review of current epidemiology, antifungal resistance, and mechanisms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Review
  2. Review
  3. Molecular Epidemiology, Antifungal Susceptibility, and Virulence Evaluation ofFrontiers in cellular and infection microbiology · 2021
    Article
  4. Candidemia due toCurrent medical mycology · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paulo Murillo NeufeldUniversidade Federal do Rio de Janeiro, Departamento de Análises Clínicas e Toxicológicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil, Departamento de Análises Clínicas e Toxicológicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil. ; Fundação Oswaldo Cruz, Instituto Nacional de Controle de Qualidade em Saúde, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brasil, Instituto Nacional de Controle de Qualidade em Saúde, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
Marcia de Souza Carvalho MelhemInstituto Adolfo Lutz, Serviço de Parasitologia, Instituto Adolfo Lutz, São Paulo, SP, Brasil, Serviço de Parasitologia, Instituto Adolfo Lutz, São Paulo, SP, Brazil.
Maria Walderez SzeszsInstituto Adolfo Lutz, Serviço de Parasitologia, Instituto Adolfo Lutz, São Paulo, SP, Brasil, Serviço de Parasitologia, Instituto Adolfo Lutz, São Paulo, SP, Brazil.
Marcos Dornelas RibeiroServiço de Patologia Clínica, Instituto Estadual de Hematologia Arthur da Siqueira Cavalcante, Rio de Janeiro, RJ, Brasil, Serviço de Patologia Clínica, Instituto Estadual de Hematologia Arthur da Siqueira Cavalcante, Rio de Janeiro, RJ, Brazil.
Efigênia de Lourdes Teixeira AmorimSetor de Microbiologia e Urinálise, Laboratório Sérgio Franco, Rio de Janeiro, RJ, Brasil, Setor de Microbiologia e Urinálise, Laboratório Sérgio Franco, Rio de Janeiro, RJ, Brazil.
Manuela da SilvaFundação Oswaldo Cruz, Instituto Nacional de Controle de Qualidade em Saúde, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brasil, Instituto Nacional de Controle de Qualidade em Saúde, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
Marcia dos Santos LazéraFundação Oswaldo Cruz, Laboratório de Micologia, Instituto de Pesquisa Clínica Hospital Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brasil, Laboratório de Micologia, Instituto de Pesquisa Clínica Hospital Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One hundred and forty-one Candida species isolated from clinical specimens of hospitalized patients in Rio de Janeiro, Brazil, during 2002 to 2007, were analized in order to evaluate the distribution and susceptibility of these species to fluconazole. Candida albicans was the most frequent species (45.4%), followed by C. parapsilosis sensu lato (28.4%), C. tropicalis (14.2%), C. guilliermondii (6.4%), C. famata (2.8%), C. glabrata (1.4%), C. krusei (0.7%) and C. lambica (0.7%). The sources of fungal isolates were blood (47.5%), respiratory tract (17.7%), urinary tract (16.3%), skin and mucous membrane (7.1%), catheter (5.6%), feces (2.1%) and mitral valve tissue (0.7%). The susceptibility test was performed using the methodology of disk-diffusion in agar as recommended in the M44-A2 Document of the Clinical and Laboratory Standards Institute (CLSI). The majority of the clinical isolates (97.2%) was susceptible (S) to fluconazole, although three isolates (2.1%) were susceptible-dose dependent (S-DD) and one of them (0.7%) was resistant (R). The S-DD isolates were C. albicans, C. parapsilosis sensu lato and C. tropicalis. One isolate of C. krusei was resistant to fluconazole. This work documents the high susceptibility to fluconazole by Candida species isolated in Rio de Janeiro, Brazil.

Indexed as

Antifungal AgentsBrazilCandidaCandidiasisCross InfectionDisk Diffusion Antimicrobial TestsDrug Resistance, FungalFluconazoleHumansAntifungal AgentsFluconazoleantifungal susceptibilityCandidadisk diffusion methodfluconazole

Identifiers

PMID26273262
PMCPMC4507539

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.