ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2015
Hypocholesterolemic effects of Kluyveromyces marxianus M3 isolated from Tibetan mushrooms on diet-induced hypercholesterolemia in rat.
Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 41 citations in OpenAlex.
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- New generation probiotics: combining probiotic and biotechnological potential of Kluyveromyces marxianus.Applied microbiology and biotechnology · 2025Article
- Safety aspects and in vitro probiotic assessment of Kluyveromyces marxianus strains from neonatal faeces.Antonie van Leeuwenhoek · 2025Article
- The Biotherapeutic Potential of a Novel ProbioticJournal of fungi (Basel, Switzerland) · 2025Article
- Wet pulverization combined with temperature cycling strategy for extraction ofFood chemistry: X · 2025Article
- Exploring the Anti-obesity Effects of Specific Medicinal Herbs: Focus on Herbal Approaches and their Role in Gut Microbiota.Current pharmaceutical biotechnology · 2025Review
- In vitro probiotic potential of lactic acid bacteria isolated from the intestines of Muscovy ducks.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- The Main Features and Microbiota Diversity of Fermented Camel Milk.Foods (Basel, Switzerland) · 2024Review
- The regulatory effects of second-generation antipsychotics on lipid metabolism: Potential mechanisms mediated by the gut microbiota and therapeutic implications.Frontiers in pharmacology · 2023Review
- Edible Mushrooms as Novel Myco-Therapeutics: Effects on Lipid Level, Obesity and BMI.Journal of fungi (Basel, Switzerland) · 2022Review
- BioprospectingFrontiers in bioengineering and biotechnology · 2022Review
- Modelling hypercholesterolaemia in rats using high cholesterol diet.International journal of experimental pathology · 2021Review
- Probiotic Properties ofFrontiers in microbiology · 2019Article
- Anti-Obesity Effects of Medicinal and Edible Mushrooms.Molecules (Basel, Switzerland) · 2018Review
- Bioactivities and Health Benefits of Mushrooms Mainly from China.Molecules (Basel, Switzerland) · 2016Review
- The Cholesterol-Lowering Effect of Alisol Acetates Based on HMG-CoA Reductase and Its Molecular Mechanism.Evidence-based complementary and alternative medicine : eCAM · 2016Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate the effects of Kluyveromyces marxianus M3 isolated from Tibetan mushrooms on diet-induced hypercholesterolemia in rats, female Wistar rats were fed a high-cholesterol diet (HCD) for 28 d to generate hyperlipidemic models. Hyperlipidemic rats were assigned to four groups, which were individually treated with three different dosages of K. marxianus M3+HCD or physiological saline+HCD via oral gavage for 28 d. The total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) levels in the serum and liver of the rats were measured using commercially available enzyme kits. In addition, the liver morphology was also examined using hematoxylin and eosin staining and optical microscopy. According to our results, the serum and liver TC, TG, LDL-C levels and atherogenic index (AI) were significantly decreased in rats orally administered K. marxianus M3 (p <0.01), and the HDL-C levels and anti atherogenic index (AAI) were significantly increased (p <0.01) compared to the control group. Moreover, K. marxianus M3 treatment also reduced the build-up of lipid droplets in the liver and exhibited normal hepatocytes, suggesting a protective effect of K. marxianus M3 in hyperlipidemic rats.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.