Evidence map›Paper›PMID 26273237›Full record

ArticleMetabolomics : Official journal of the Metabolomic Society2015

Untargeted metabolomics studies employing NMR and LC-MS reveal metabolic coupling between

Timothy Hamerly, Brian P Tripet, Michelle Tigges, Richard J Giannone, Louie Wurch, Robert L Hettich, Mircea Podar, Valerie Copié, Brian Bothner

Abstract read
In one paragraph

Article in Metabolomics : Official journal of the Metabolomic Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. PepT1-knockout mice harbor a protective metabolome beneficial for intestinal wound healing.American journal of physiology. Gastrointestinal and liver physiology · 2021
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. A Complex Endomembrane System in the ArchaeonFrontiers in microbiology · 2017
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Timothy HamerlyDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717.
Brian P TripetDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717.
Michelle TiggesDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717.
Richard J GiannoneOak Ridge National Laboratory, Oak Ridge, TN 37831.
Louie WurchOak Ridge National Laboratory, Oak Ridge, TN 37831 ; Department of Microbiology, University of Tennessee, Knoxville, TN 37996.
Robert L HettichOak Ridge National Laboratory, Oak Ridge, TN 37831.
Mircea PodarOak Ridge National Laboratory, Oak Ridge, TN 37831 ; Department of Microbiology, University of Tennessee, Knoxville, TN 37996.
Valerie CopiéDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717 ; Thermal Biology Institute, Montana State University, Bozeman, MT 59717.
Brian BothnerDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717 ; Thermal Biology Institute, Montana State University, Bozeman, MT 59717.

Funding

Center for the Analysis of Cellular Mechanisms and Systems BiologyP20GM103394 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI DRATZ, EDWARD A · 2012 to 2013
$3.2M
Acquisition of a 600 MHz NMR cryoprobe and 600 MHz spectrometer console upgradeS10RR026659 · NCRR · MONTANA STATE UNIVERSITY - BOZEMAN · PI COPIE, VALERIE · 2011 to 2011
$600k
NCRR NIH HHS S10 RR026659NIGMS NIH HHS P20 GM103394
6 · The paper itself

Abstract

Interspecies interactions are the basis of microbial community formation and infectious diseases. Systems biology enables the construction of complex models describing such interactions, leading to a better understanding of disease states and communities. However, before interactions between complex organisms can be understood, metabolic and energetic implications of simpler real-world host-microbe systems must be worked out. To this effect, untargeted metabolomics experiments were conducted and integrated with proteomics data to characterize key molecular-level interactions between two hyperthermophilic microbial species, both of which have reduced genomes. Metabolic changes and transfer of metabolites between the archaea

Indexed as

hyperthermophilic ArchaeaIgnicoccus hospitalisinterspecies interactionsLC-MSmetabolic pathway analysismetabolomicsNanoarcheum equitansNMRsystems biology

Identifiers

PMID26273237
PMCPMC4529127

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.