Evidence map›Paper›PMID 26273112›Full record

ArticleTetrahedron2015

Gold(I)-catalyzed enantioselective [3+2] and [3+3] cycloaddition reactions of propargyl acetals/ketals.

Cristina Navarro, Nathan D Shapiro, Maurizio Bernasconi, Takahiro Horibe, F Dean Toste

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tetrahedron, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 25 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cristina NavarroDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
Nathan D ShapiroDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
Maurizio BernasconiDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
Takahiro HoribeDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
F Dean TosteDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
University of California, Berkeley · US

Funding

Catalytic Methods for Carbon-Carbon Bond FormationR01GM073932 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI TOSTE, F. DEAN · 2005 to 2014
$2.5M
NIGMS NIH HHS R01 GM073932
6 · The paper itself

Abstract

An asymmetric gold(I)-catalyzed [3+2] cycloaddition of propargyl acetals/ketals and aldehydes is reported, which proceeds via stepwise migration-fragmentation of acetals/ketals and cycloaddition of the in situ generated gold-carbenoid intermediate. Various functionalized 2, 5-dihydrofurans were obtained in good yields and high enantioselectivities. Furthermore, an example of the first gold(I) catalyzed [3+3] cycloaddition of secondary propargyl ketals and nitrones is presented.

Indexed as

CycloadditionEnantioselective catalysisGoldHomogeneous catalysisPropargyl acetals/ketals

Identifiers

PMID26273112
PMCPMC4528387
OpenAlexW323746790

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.