Evidence map›Paper›PMID 26272688›Full record

SynthesisJournal of minimally invasive gynecology2016

Robotic Versus Laparoscopic Hysterectomy for Benign Disease: A Systematic Review and Meta-Analysis of Randomized Trials.

Benjamin B Albright, Tilman Witte, Alena N Tofte, Jeremy Chou, Jonathan D Black, Vrunda B Desai, Elisabeth A Erekson

Open access · greenAbstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of minimally invasive gynecology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 6 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 6 syntheses or guidelines pooled it, 138 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Robotic Surgery in Australasian Gynaecology: Results of a 2025 Cross-Sectional Survey.The Australian & New Zealand journal of obstetrics & gynaecology · 2026
    Article
  8. Review
  9. Article
  10. Impact of age on postoperative outcomes in laparoscopic hysterectomy for endometriosis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Robotic-assisted hysterectomy using DEXTERFacts, views & vision in ObGyn · 2025
    Article
  16. Robotic versus open hysterectomy for very large uterus (more than 1000 g): A bicentric retrospective study of 150 patients.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Benjamin B AlbrightDartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Hanover, NH; Yale University School of Medicine, New Haven, CT. Electronic address: benjamin.b.albright.gr@dartmouth.edu.
Tilman WitteDartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Hanover, NH; Institute for Community Medicine, University of Greifswald, Greifswald, Germany.
Alena N TofteDartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Hanover, NH.
Jeremy ChouDartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Hanover, NH.
Jonathan D BlackObstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT.
Vrunda B DesaiObstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT.
Elisabeth A EreksonDartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Hanover, NH; Department of Obstetrics and Gynecology, Geisel School of Medicine at Dartmouth, Hanover, NH.
Dartmouth Institute for Health Policy and Clinical Practice · USDartmouth College · USYale University · US

Funding

SYNERGY: The Dartmouth Center for clinical and Translational ScienceUL1TR001086 · NCATS · DARTMOUTH COLLEGE · PI GREEN, ALAN I · 2013 to 2017
$18.3M
SYNERGY: The Dartmouth Center for clinical and Translational ScienceKL2TR001088 · NCATS · DARTMOUTH COLLEGE · PI GREEN, ALAN I · 2013 to 2017
$3.3M
NCATS NIH HHS KL2 TR001088NCATS NIH HHS KL2TR001088NCATS NIH HHS UL1 TR001086
6 · The paper itself

Abstract

We conducted a systematic review and meta-analysis to assess the safety and effectiveness of robotic vs laparoscopic hysterectomy in women with benign uterine disease, as determined by randomized studies. We searched MEDLINE, EMBASE, the Cochrane Library, ClinicalTrials.gov, and Controlled-Trials.com from study inception to October 9, 2014, using the intersection of the themes "robotic" and "hysterectomy." We included only randomized and quasi-randomized controlled trials of robotic vs laparoscopic hysterectomy in women for benign disease. Four trials met our inclusion criteria and were included in the analyses. We extracted data, and assessed the studies for methodological quality in duplicate. For meta-analysis, we used random effects to calculate pooled risk ratios (RRs) and weighted mean differences. For our primary outcome, we used a modified version of the Expanded Accordion Severity Grading System to classify perioperative complications. We identified 41 complications among 326 patients. Comparing robotic and laparoscopic hysterectomy, revealed no statistically significant differences in the rate of class 1 and 2 complications (RR, 0.66; 95% confidence interval [CI], 0.23-1.89) or in the rate of class 3 and 4 complications (RR, 0.99; 95% CI, 0.22-4.40). Analyses of secondary outcomes were limited owing to heterogeneity, but showed no significant benefit of the robotic technique over the laparoscopic technique in terms of length of hospital stay (weighted mean difference, -0.39 day; 95% CI, -0.92 to 0.14 day), total operating time (weighted mean difference, 9.0 minutes; 95% CI, -31.27 to 47.26 minutes), conversions to laparotomy, or blood loss. Outcomes of cost, pain, and quality of life were reported inconsistently and were not amenable to pooling. Current evidence demonstrates neither statistically significant nor clinically meaningful differences in surgical outcomes between robotic and laparoscopic hysterectomy for benign disease. The role of robotic surgery in benign gynecology remains unclear.

Indexed as

HysterectomyLaparoscopyRobotic Surgical ProceduresFemaleHumansLength of StayMiddle AgedQuality of LifeRandomized Controlled Trials as TopicUterine Cervical DiseasesLaparoscopic hysterectomyMeta-analysisRobotic surgerySystematic review

Identifiers

PMID26272688
PMCPMC4698211
OpenAlexW1195649932

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.