Evidence map›Paper›PMID 26272384›Full record

ReviewStroke2015

Modeling Ischemia in the Immature Brain: How Translational Are Animal Models?

Carina Mallard, Zinaida S Vexler

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Stroke, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carina MallardFrom the Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden (C.M.); and Department of Neurology, University California San Francisco (Z.S.V.).
Zinaida S VexlerFrom the Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden (C.M.); and Department of Neurology, University California San Francisco (Z.S.V.). Zena.Vexler@ucsf.edu.

Funding

Neonatal Stroke: The Role of Microglia-derived Extracellular VesiclesR01NS044025 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VEXLER, ZINAIDA S · 2002 to 2023
$7.7M
Macrophages as modulators of repair after neonatal strokeR01NS076726 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VEXLER, ZINAIDA S · 2012 to 2016
$1.8M
Blood-brain barrier function after neonatal and pediatric experimental strokeR21NS080015 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VEXLER, ZINAIDA S · 2012 to 2013
$445k
NINDS NIH HHS NS080015NINDS NIH HHS NS44025NINDS NIH HHS NS76726NINDS NIH HHS R01 NS044025NINDS NIH HHS R01 NS076726NINDS NIH HHS R21 NS080015
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Asphyxia NeonatorumBrain IschemiaDisease Models, AnimalHypoxia-Ischemia, BrainTranslational Research, BiomedicalAnimalsAnimals, NewbornHumansInfant, NewbornInfant, PrematureRabbitsRatsSheepSwinehypoxia-ischemia, brainimmune, innateinfant, newborninfarction, middle cerebral arteryinflammationpreterm birthstroke

Identifiers

PMID26272384
PMCPMC4589478

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.