ReviewNature reviews. Immunology2015
Making the case for chromatin profiling: a new tool to investigate the immune-regulatory landscape.
Review in Nature reviews. Immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Hypermethylation at the CXCR5 gene locus limits trafficking potential of CD8+ T cells into B-cell follicles during HIV-1 infection.Blood advances · 2022Article
- Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses.Genome medicine · 2021Article
- A Beginner's Guide to Analysis of RNA Sequencing Data.American journal of respiratory cell and molecular biology · 2018Article
- Thinking BIG rheumatology: how to make functional genomics data work for you.Arthritis research & therapy · 2018Review
- Pregnancy Epigenetic Signature in T Helper 17 and T Regulatory Cells in Multiple Sclerosis.Frontiers in immunology · 2018Article
- The origins of memory T cells.Nature · 2017Article
- Epigenetic landscapes reveal transcription factors that regulate CD8Nature immunology · 2017Article
- Chromatin landscapes and genetic risk for juvenile idiopathic arthritis.Arthritis research & therapy · 2017Article
- Rapid Recall Ability of Memory T cells is Encoded in their Epigenome.Scientific reports · 2017Article
- Genome-Wide Approaches to Defining Macrophage Identity and Function.Microbiology spectrum · 2016Review
- Mathematical Models for Immunology: Current State of the Art and Future Research Directions.Bulletin of mathematical biology · 2016Review
- Review
- Insights into the pathogenesis of Langerhans cell histiocytosis: the development of targeted therapies.ImmunoTargets and therapy · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Recent technological advances have enabled researchers to accurately and efficiently assay the chromatin dynamics of scarce cell populations. In this Opinion article, we advocate the application of these technologies to central questions in immunology. Unlike changes to other molecular structures in the cell, chromatin features can reveal the past (developmental history), present (current activity) and future (potential response to challenges) of a given immune cell type; chromatin profiling is therefore an important new tool for studying the immune-regulatory networks of health and disease.
Indexed as
Identifiers
26272294What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.