Evidence map›Paper›PMID 26272187›Full record

ReviewCurrent heart failure reports2015

Novel Biomarker Approaches for Managing Patients With Cardiac Transplantation.

Peter J Kennel, P Christian Schulze

Abstract readReview
In one paragraph

Review in Current heart failure reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Osteopontin and Transplantation: Where Are We Now?Archivum immunologiae et therapiae experimentalis · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peter J KennelDivision of Cardiology, Department of Medicine, Columbia University Medical Center, 622 West 168th Street, PH 10, Room 203, New York, NY, 10032, USA.
P Christian SchulzeDivision of Cardiology, Department of Medicine, Columbia University Medical Center, 622 West 168th Street, PH 10, Room 203, New York, NY, 10032, USA. pcs2121@cumc.columbia.edu.

Funding

Cardiac Lipotoxicity and Ceramide Metabolism in Heart FailureR01HL114813 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI COLOMBO, PAOLO C, SCHULZE, P. CHRISTIAN · 2013 to 2017
$3.0M
NHLBI NIH HHS R01 HL114813
6 · The paper itself

Abstract

Despite major advances in the medical care of patients following heart transplantation (HTx) and a steady increase in long-term survival, allograft surveillance is still based on endomyocardial biopsy, the gold standard since the 1970s. This invasive procedure calls for less burdening and more cost-effective approaches. In recent years, impressive progress has been made in utilizing blood-based biomarkers for the diagnosis and management of diseases in a variety of fields. Hence, a number of trials have been performed testing the usefulness of circulating molecules or other technical methods to overcome the need for surveillance myocardial biopsy in HTx patients. Here, we review current approaches and the state of research on novel biomarkers for the management of patients following heart transplantation.

Indexed as

Heart TransplantationBiomarkersBlood ProteinsDNAGraft RejectionHumansNatriuretic Peptide, BrainPostoperative CareRNATroponinBiomarkersBlood ProteinsDNANatriuretic Peptide, BrainRNATroponinBiomarkerHeart transplantationMicroRNARejectionSurvivalTransplantation biology

Identifiers

PMID26272187
PMCPMC6752034

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.