Evidence map›Paper›PMID 26272169›Full record

ArticleJournal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie2015

Longitudinal relationship between insulin-like growth factor-1 levels and vertical facial growth.

Mohamed I Masoud, Hussain Y A Marghalani, Najlaa M Alamoudi, Douaa El Derw, Ibrahim M Masoud, Nour F Gowharji

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Article in Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

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0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Can IGF-1 serve as a reliable skeletal maturity indicator? A meta-analysis.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohamed I MasoudDepartment of Developmental Biology, Harvard School of Dental Medicine, 188 Longwood Ave, 02115, Boston, MA, USA. mohamed_masoud@hsdm.harvard.edu.
Hussain Y A MarghalaniDepartment of Orthodontics, King Abdulaziz University, Jeddah, Saudi Arabia.
Najlaa M AlamoudiPediatric Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.
Douaa El DerwPediatric Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.
Ibrahim M MasoudDr. Ibrahim Masoud's Dental Specialty Clinic, Jeddah, Saudi Arabia.
Nour F GowharjiDepartment of Pediatric Dentistry, Tufts School of Dental Medicine, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFacial growth in the vertical dimension is the last to be completed and can often be detrimental to the success of dental implants, orthodontic treatment, and orthognathic surgery that young individuals undergo.

aimThe purpose of this study was to evaluate the longitudinal relationship between changes in total anterior facial height and insulin-like growth factor-1 (IGF-1) levels measured using blood-spot samples.

methodsOur sample included 25 orthodontic patients from whom we had access to annual lateral cephalometric radiographs and IGF-1 measurements. Each subject was observed between 2 and 6 times, resulting in 43 annual intervals from a total of 77 observations.

resultsWe noted a significant moderate positive correlation (+ 0.48) between the percentage of change in blood-spot IGF-1 levels and the percentage of change in total anterior face height (p = 0.01).

conclusionLongitudinal changes in IGF-1 levels can be used to predict a patient's vertical facial growth. There was no significant correlation between changes in vertical facial development and a single cross-sectional IGF-1 measurement.

Indexed as

Vertical DimensionAdolescentAgingCephalometryChildFaceFemaleHumansInsulin-Like Growth Factor ILongitudinal StudiesMaleMaxillofacial DevelopmentRadiography, DentalReproducibility of ResultsSensitivity and SpecificityYoung AdultInsulin-Like Growth Factor ICraniofacial biologyDental implantsDevelopmental biologyGrowth predictionOrthognathics

Identifiers

PMID26272169

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.