ArticleFish physiology and biochemistry2015
Effect of temperature and diet on wound healing in Atlantic salmon (Salmo salar L.).
Article in Fish physiology and biochemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 79 citations in OpenAlex.
- Chromatophores and their role in the healing process of the integument of Gymnotus carapo (Teleostei: Gymnotiformes).Journal of molecular histology · 2026Article
- Immune gene expression in salmon keratocytes upon bacterial exposure.BMC molecular and cell biology · 2025Article
- Histological and Transcriptomic Characterization of Full-Thickness Skin Wound Healing in Maraena Whitefish (International journal of molecular sciences · 2025Article
- The costs and healing rates of minor injuries in neonatal reef sharks.Journal of fish biology · 2025Article
- Sea lice (Frontiers in genetics · 2025Article
- Embryonic Temperature Influences the Mucosal Responses of Atlantic Salmon Alevins to a Bacterial Challenge.Marine biotechnology (New York, N.Y.) · 2024Article
- Evaluation of Post-Surgical Recovery in Olive Flounder (Animals : an open access journal from MDPI · 2024Article
- Histological and ultrastructural characterization of the dorso-ventral skin of the juvenile and the adult starry puffer fish (Arothron stellatus, Anonymous 1798).BMC veterinary research · 2023Article
- Integrative biology of injury in animals.Biological reviews of the Cambridge Philosophical Society · 2023Review
- Quantifying changes in umbilicus size to estimate the relative age of neonatal blacktip reef sharks (Conservation physiology · 2023Article
- Chronic stress negatively impacts wound healing, welfare, and stress regulation in internally tagged Atlantic salmon (Frontiers in physiology · 2023Article
- Optimisation of trace mineral supplementation in diets for Atlantic salmon smolt with reference to holistic fish performance in terms of growth, health, welfare, and potential environmental impacts.Frontiers in physiology · 2023Article
- Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar).Journal of fish diseases · 2022Article
- Transport and Barrier Functions in Rainbow Trout Trunk Skin Are Regulated by Environmental Salinity.Frontiers in physiology · 2022Article
- Skin Wound Healing Rate in Fish Depends on Species and Microbiota.International journal of molecular sciences · 2021Article
- Dietary administration of the probiotic Shewanella putrefaciens to experimentally wounded gilthead seabream (Sparus aurata L.) facilitates the skin wound healing.Scientific reports · 2020Article
- Wound healing in post-smolt Atlantic salmon (Salmo salar L.).Scientific reports · 2019Article
- High fish density delays wound healing in Atlantic salmon (Salmo salar).Scientific reports · 2018Article
- Atlantic salmon skin barrier functions gradually enhance after seawater transfer.Scientific reports · 2018Article
- Chronic wounds alter the proteome profile in skin mucus of farmed gilthead seabream.BMC genomics · 2017Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Compromised skin integrity of farmed Atlantic salmon, commonly occurring under low temperature and stressful conditions, has major impacts on animal welfare and economic productivity. Even fish with minimal scale loss and minor wounds can suffer from secondary infections, causing downgrading and mortalities. Wound healing is a complex process, where water temperature and nutrition play key roles. In this study, Atlantic salmon (260 g) were held at different water temperatures (4 or 12 °C) and fed three different diets for 10 weeks, before artificial wounds were inflicted and the wound healing process monitored for 2 weeks. The fish were fed either a control diet, a diet supplemented with zinc (Zn) or a diet containing a combination of functional ingredients in addition to Zn. The effect of diet was assessed through subjective and quantitative skin histology and the transcription of skin-associated chemokines. Histology confirmed that wound healing was faster at 12 °C. The epidermis was more organised, and image analyses of digitised skin slides showed that fish fed diets with added Zn had a significantly larger area of the epidermis covered by mucous cells in the deeper layers after 2 weeks, representing more advanced healing progression. Constitutive levels of the newly described chemokines, herein named CK 11A, B and C, confirmed their preferential expression in skin compared to other tissues. Contrasting modulation profiles at 4 and 12 °C were seen for all three chemokines during the wound healing time course, while the Zn-supplemented diets significantly increased the expression of CK 11A and B during the first 24 h of the healing phase.
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