Evidence map›Paper›PMID 26271827›Full record

ArticleVaccine2015

Incidence of medically attended influenza infection and cases averted by vaccination, 2011/2012 and 2012/2013 influenza seasons.

Michael L Jackson, Lisa A Jackson, Burney Kieke, David McClure, Manjusha Gaglani, Kempapura Murthy, Ryan Malosh, Arnold Monto, Richard K Zimmerman, Ivo M Foppa and 2 more

Abstract read
In one paragraph

Article in Vaccine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Michael L JacksonGroup Health Research Institute, Seattle, WA, United States. Electronic address: jackson.ml@ghc.org.
Lisa A JacksonGroup Health Research Institute, Seattle, WA, United States.
Burney KiekeMarshfield Clinic Research Foundation, Marshfield, WI, United States.
David McClureMarshfield Clinic Research Foundation, Marshfield, WI, United States.
Manjusha GaglaniBaylor Scott & White Health and Texas A&M University Health Science Center College of Medicine, Temple, TX, United States.
Kempapura MurthyBaylor Scott & White Health and Texas A&M University Health Science Center College of Medicine, Temple, TX, United States.
Ryan MaloshUniversity of Michigan School of Public Health, Ann Arbor, MI, United States.
Arnold MontoUniversity of Michigan School of Public Health, Ann Arbor, MI, United States.
Richard K ZimmermanUniversity of Pittsburgh, Pittsburgh, PA, United States.
Ivo M FoppaCenters for Disease Control and Prevention, Atlanta, GA, United States; Batelle, Atlanta, GA, United States.
Brendan FlanneryCenters for Disease Control and Prevention, Atlanta, GA, United States.
Mark G ThompsonCenters for Disease Control and Prevention, Atlanta, GA, United States.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Core_plus Option_A_C_Influenza Surveillance and Vaccine Effectiveness in a LargeU01IP000467 · IP · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZIMMERMAN, RICHARD K · 2011 to 2015
$5.9M
Core_Prospective population-based estimation of influenza vaccine effectiveness aU01IP000466 · IP · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI JACKSON, MICHAEL L · 2011 to 2015
$4.1M
NCATS NIH HHS UL1 TR001857NCIRD CDC HHS U01 IP000466NCIRD CDC HHS U01 IP000467
6 · The paper itself

Abstract

backgroundWe estimated the burden of outpatient influenza and cases prevented by vaccination during the 2011/2012 and 2012/2013 influenza seasons using data from the United States Influenza Vaccine Effectiveness (US Flu VE) Network.

methodsWe defined source populations of persons who could seek care for acute respiratory illness (ARI) at each of the five US Flu VE Network sites. We identified all members of the source population who were tested for influenza during US Flu VE influenza surveillance. Each influenza-positive subject received a sampling weight based on the proportion of source population members who were tested for influenza, stratified by site, age, and other factors. We used the sampling weights to estimate the cumulative incidence of medically attended influenza in the source populations. We estimated cases averted by vaccination using estimates of cumulative incidence, vaccine coverage, and vaccine effectiveness.

resultsCumulative incidence of medically attended influenza ranged from 0.8% to 2.8% across sites during 2011/2012 and from 2.6% to 6.5% during the 2012/2013 season. Stratified by age, incidence ranged from 1.2% among adults 50 years of age and older in 2011/2012 to 10.9% among children 6 months to 8 years of age in 2012/2013. Cases averted by vaccination ranged from 4 to 41 per 1000 vaccinees, depending on the study site and year.

conclusionsThe incidence of medically attended influenza varies greatly by year and even by geographic region within the same year. The number of cases averted by vaccination varies greatly based on overall incidence and on vaccine coverage.

Indexed as

Office VisitsAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHumansIncidenceInfantInfluenza, HumanInfluenza VaccinesMaleMiddle AgedTopography, MedicalInfluenza VaccinesIncidenceInfluenza, humanInfluenza vaccines

Identifiers

PMID26271827
PMCPMC5843472

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.