Evidence map›Paper›PMID 26271454›Full record

ReviewEuropean child & adolescent psychiatry2015

ESCAP Expert Article: borderline personality disorder in adolescence: an expert research review with implications for clinical practice.

Peter Fonagy, Mario Speranza, Patrick Luyten, Michael Kaess, Christel Hessels, Martin Bohus

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in European child & adolescent psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05162287 (Psychosocial Distress, Levels of Personality Functioning, and Social Withdrawal in a Child and Adolescent Psychiatric Acute Inpatient Population), which is not on this map. Cited by 52 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 3 pooled it
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05162287 completednot on this mapstarted 2021, after this paper: background citation

Psychosocial Distress, Levels of Personality Functioning, and Social Withdrawal in a Child and Adolescent Psychiatric Acute Inpatient Population

TypeobservationalSponsorUniversitätsklinikum Hamburg-EppendorfRan2021 to 2022Enrolled62ConditionsPersonality Disorders, Social Withdrawal of Childhood or Adolescence, Psychosocial Impairment
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 3 syntheses or guidelines pooled it, 148 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 6 countries.

Peter FonagyResearch Department of Clinical, Educational and Health Psychology, University College London, Gower Street, London, WC1E 6BT, UK. p.fonagy@ucl.ac.uk.ORCID http://orcid.org/0000-0003-0229-0091
Mario SperanzaDepartment of Child and Adolescent Psychiatry, Versailles General Hospital, Faculty of Health Sciences, Research Unit EA4047, University of Versailles Saint-Quentin-en-Yvelines, 177 rue de Versailles, 78157, Le Chesnay, France.
Patrick LuytenResearch Department of Clinical, Educational and Health Psychology, University College London, Gower Street, London, WC1E 6BT, UK.
Michael KaessDepartment of Child and Adolescent Psychiatry, Centre for Psychosocial Medicine, University of Heidelberg, Blumenstrasse 8, 69115, Heidelberg, Germany.
Christel HesselsExpertise Centre for Personality Disorders, GGz Centraal, PO Box 3051, 3800 DB, Amersfoort, The Netherlands.
Martin BohusDepartment of Psychosomatics and Psychotherapy, Central Institute of Mental Health Mannheim, Heidelberg University, J5, 68159, Mannheim, Germany.
GGz centraal · NLHeidelberg University · DEUCL Australia · AUUniversité de Versailles Saint-Quentin-en-Yvelines · FRUniversity College London · GBUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Borderline personality disorder (BPD) has onset in adolescence, but is typically first diagnosed in young adulthood. This paper provides a narrative review of the current evidence on diagnosis, comorbidity, phenomenology and treatment of BPD in adolescence. Instruments available for diagnosis are reviewed and their strengths and limitations discussed. Having confirmed the robustness of the diagnosis and the potential for its reliable clinical assessment, we then explore current understandings of the mechanisms of the disorder and focus on neurobiological underpinnings and research on psychological mechanisms. Findings are accumulating to suggest that adolescent BPD has an underpinning biology that is similar in some ways to adult BPD but differs in some critical features. Evidence for interventions focuses on psychological therapies. Several encouraging research studies suggest that early effective treatment is possible. Treatment development has just begun, and while adolescent-specific interventions are still in the process of evolution, most existing therapies represent adaptations of adult models to this developmental phase. There is also a significant opportunity for prevention, albeit there are few data to date to support such initiatives. This review emphasizes that there can be no justification for failing to make an early diagnosis of this enduring and pervasive problem.

Indexed as

AdolescentAdultBorderline Personality DisorderComorbidityFemaleHumansMalePsychotherapyTreatment OutcomeUnited NationsAdolescenceBorderline personality disorderNeurobiologyPharmacotherapyPsychotherapy

Identifiers

PMID26271454
OpenAlexW1958667601

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.