ArticlePhysics in medicine and biology2015
Mechanical contrast in spectroscopic magnetomotive optical coherence elastography.
Article in Physics in medicine and biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026Review
- Magnetic particles in motion: magneto-motive imaging and sensing.Theranostics · 2022Review
- Analysis of sensitivity in quantitative micro-elastography.Biomedical optics express · 2021Article
- Biomechanical sensing ofTheranostics · 2021Article
- Single-shot two-dimensional spectroscopic magnetomotive optical coherence elastography with graphics processing unit acceleration.Optics letters · 2020Article
- Interstitial magnetic thermotherapy dosimetry based on shear wave magnetomotive optical coherence elastography.Biomedical optics express · 2019Article
- Magnetomotive Displacement of the Tympanic Membrane Using Magnetic Nanoparticles: Toward Enhancement of Sound Perception.IEEE transactions on bio-medical engineering · 2018Article
- Effect of divalent ions and a polyphosphate on composition, structure, and stiffness of simulated drinking water biofilms.NPJ biofilms and microbiomes · 2018Article
- Optical coherence elastography - OCT at work in tissue biomechanics [Invited].Biomedical optics express · 2017Review
- Magnetic and Plasmonic Contrast Agents in Optical Coherence Tomography.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics SocietyArticle
- Magnetomotive Optical Coherence Elastography for Magnetic Hyperthermia Dosimetry Based on Dynamic Tissue Biomechanics.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics SocietyArticle
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Authors and funding
6 authors.
Funding
Abstract
The viscoelastic properties of tissues are altered during pathogenesis of numerous diseases and can therefore be a useful indicator of disease status and progression. Several elastography studies have utilized the mechanical frequency response and the resonance frequencies of tissue samples to characterize their mechanical properties. However, using the resonance frequency as a source of mechanical contrast in heterogeneous samples is complicated because it not only depends on the viscoelastic properties but also on the geometry and boundary conditions. In an elastography technique called magnetomotive optical coherence elastography (MM-OCE), the controlled movement of magnetic nanoparticles (MNPs) within the sample is used to obtain the mechanical properties. Previous demonstrations of MM-OCE have typically used point measurements in elastically homogeneous samples assuming a uniform concentration of MNPs. In this study, we evaluate the feasibility of generating MM-OCE elastograms in heterogeneous samples based on a spectroscopic approach which involves measuring the magnetomotive response at different excitation frequencies. Biological tissues and tissue-mimicking phantoms with two elastically distinct regions placed in side-by-side and bilayer configurations were used for the experiments, and finite element method simulations were used to validate the experimental results.
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