Evidence map›Paper›PMID 26271027›Full record

ArticleAnimal science journal = Nihon chikusan Gakkaiho2016

Association of a single nucleotide polymorphism in the 5' upstream region of the porcine myosin heavy chain 4 gene with meat quality traits in pigs.

Eun-Seok Cho, Kyung-Tai Lee, Jun-Mo Kim, Si-Woo Lee, Hyeon-Jeong Jeon, Seung-Hwan Lee, Ki-Chang Hong, Tae-Hun Kim

Open access · hybridAbstract read
In one paragraph

Article in Animal science journal = Nihon chikusan Gakkaiho, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Eun-Seok ChoAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Suwon, Korea.
Kyung-Tai LeeAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Suwon, Korea.
Jun-Mo KimDivision of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Korea.
Si-Woo LeeAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Suwon, Korea.
Hyeon-Jeong JeonAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Suwon, Korea.
Seung-Hwan LeeHanwoo Research Institute, National Institute of Animal Science, RDA, Pyeongchang, Korea.
Ki-Chang HongDivision of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Korea.
Tae-Hun KimAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Suwon, Korea.
National Institute of Animal Science · KRKorea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We identified a potential molecular marker associated with meat quality traits in the myosin heavy chain 4, MYH4 gene of Landrace pigs. Sequencing revealed a single nucleotide polymorphism (SNP; g.-1398G>T) in the 5' upstream region of MYH4. It was significantly associated with the number of type IIa muscle fibers and water-holding capacity based on filter-paper fluid uptake. The GG genotype groups had a greater number of type IIa fibers and a larger area composed of type IIa fibers than the other genotype group (P = 0.004 and P = 0.061, respectively). Expression level of MYH4 gene in the genotype TT or GT was higher than in genotype of GG (P < 0.0001). The T allele may enhance expression level of MYH4 gene and then the portion of IIb type fiber in the muscle be increased by the T allelle. Therefore, we suggest that the g.-1398G>T in the 5' upstream region of the porcine MYH4 may be used as a molecular marker for meat quality traits, although its functional effect is not defined yet.

Indexed as

Food QualityMeatAllelesAnimalsBody WaterGene ExpressionGenetic Association StudiesGenetic MarkersGenotypeMuscle Fibers, SkeletalMyosin Heavy ChainsPolymorphism, Single NucleotideSwineGenetic MarkersMyosin Heavy Chainsmeat qualitymuscle fiber compositionmyosin heavy chain 4 genepigsingle nucleotide polymorphism

Identifiers

PMID26271027
PMCPMC5042030
OpenAlexW1925619313

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.