Evidence map›Paper›PMID 26270662›Full record

ReviewInternational journal of molecular sciences2015

New Immunosuppressive Therapies in Uveitis Treatment.

Salvador Mérida, Elena Palacios, Amparo Navea, Francisco Bosch-Morell

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. SARS-CoV-2 vaccination and uveitis: Are they linked?Annals of medicine and surgery (2012) · 2022
    Review
  7. Sympathetic ophthalmia: A comprehensive update.Indian journal of ophthalmology · 2022
    Review
  8. Article
  9. Role of interferons in diabetic retinopathy.World journal of diabetes · 2021
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Update in treatment of uveitic macular edema.Drug design, development and therapy · 2019
    Review
  15. Review
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Salvador MéridaInstituto de Ciencias Biomédicas, Universidad CEU Cardenal Herrera, Valencia 46113, Spain. salvador.merida@uch.ceu.es.
Elena PalaciosOftalmología Médica, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana, Valencia 46020, Spain. eleofta@hotmail.com.
Amparo NaveaInstituto de Ciencias Biomédicas, Universidad CEU Cardenal Herrera, Valencia 46113, Spain. eleofta@hotmail.com.
Francisco Bosch-MorellInstituto de Ciencias Biomédicas, Universidad CEU Cardenal Herrera, Valencia 46113, Spain. fbosch@uch.ceu.es.
Universidad Cardenal Herrera CEU · ESFundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uveitis is an inflammatory process that initially starts in the uvea, but can also affect other adjacent eye structures, and is currently the fourth cause of blindness in developed countries. Corticoids are probably the most widespread treatment, but resorting to other immunosuppressive treatments is a frequent practice. Since the implication of different cytokines in uveitis has been well demonstrated, the majority of recent treatments for this disease include inhibitors or antibodies against these. Nevertheless, adequate treatment for each uveitis type entails a difficult therapeutic decision as no clear recommendations are found in the literature, despite the few protocolized clinical assays and many case-control studies done. This review aims to present, in order, the mechanisms and main indications of the most modern immunosuppressive drugs against cytokines.

Indexed as

Adrenal Cortex HormonesAnimalsAntibodies, MonoclonalCytokinesEyeHumansImmunologic FactorsImmunosuppressive AgentsT-Lymphocytes, Helper-InducerT-Lymphocyte SubsetsUveitisAdrenal Cortex HormonesAntibodies, MonoclonalCytokinesImmunologic FactorsImmunosuppressive Agentsantibodycorticoidscytokinesimmunosuppressiveuveitis

Identifiers

PMID26270662
PMCPMC4581271
OpenAlexW2143952905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.