Evidence map›Paper›PMID 26270655›Full record

ReviewCurrent opinion in infectious diseases2015

Innate-like lymphocytes in intestinal infections.

Michael S Bennett, June L Round, Daniel T Leung

Abstract readReview
In one paragraph

Review in Current opinion in infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. ControllingInfection and immunity · 2024
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Gut Innate Immunity and HIV Pathogenesis.Current HIV/AIDS reports · 2021
    Review
  8. Review
  9. Review
  10. From Initiators to Effectors: Roadmap Through the Intestine During Encounter ofFrontiers in cellular and infection microbiology · 2020
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael S BennettaDepartment of Medicine, Division of Infectious Diseases bDepartment of Pathology, Division of Microbiology and Immunology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
June L Round
Daniel T Leung

Funding

Immune Responses to Vibrio Cholerae in ChildrenK08AI100923 · NIAID · UNIVERSITY OF UTAH · PI LEUNG, DANIEL TED · 2012 to 2016
$686k
NIAID NIH HHS K08 AI100923NIAID NIH HHS K08AI100923
6 · The paper itself

Abstract

purpose of reviewThe mechanisms of immunity against intestinal pathogens are not well understood. Innate-like lymphocytes are a group of recently discovered cells that do not fit into either side of the historical innate-adaptive classification. They are enriched in the intestinal mucosa and participate in gut homeostasis and defense against infections. We will review recent developments in innate-like T lymphocytes and innate lymphoid cells, specifically as they relate to responses to intestinal infections. RECENT

findingsRecent studies have uncovered further details into antigen presentation to γδ T cells and mucosal-associated invariant T cells, the role of invariant natural killer T cells and mucosal-associated invariant T cells in intestinal infections, and how innate lymphoid cells maintain gut homeostasis and protection. SUMMARY: Innate-like lymphocytes play a major role in the critical early response to intestinal infections and maintaining gut homeostasis. Further studies of the roles these cells play in the human intestinal mucosa will aid in the development of therapeutics against intestinal infections.

Indexed as

AnimalsBacterial InfectionsHumansImmunity, InnateIntestinal DiseasesMiceT-Lymphocytes

Identifiers

PMID26270655
PMCPMC4925623

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.