Evidence map›Paper›PMID 26270594›Full record

ArticleMemorias do Instituto Oswaldo Cruz2015

Effects of penicillin and erythromycin on adherence of invasive and noninvasive isolates of Streptococcus pyogenes to laminin.

Aleksandra Šmitran, Dragana Vuković, Ina Gajić, Jelena Marinković, Lazar Ranin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Memorias do Instituto Oswaldo Cruz, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aleksandra ŠmitranDepartment of Microbiology and Immunology, Faculty of Medicine, University of Banja Luka, Banja Luka, Republic of Srpska, BA.
Dragana VukovićInstitute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, RS.
Ina GajićInstitute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, RS.
Jelena MarinkovićInstitute of Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, Belgrade, RS.
Lazar RaninInstitute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, RS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the possible relationship between the invasiveness of group A Streptococcus (GAS) strains and their abilities to adhere to laminin and assessed the effects of subinhibitory concentrations of penicillin and erythromycin on the ability of GAS to adhere to laminin. The adherence of noninvasive and highly invasive isolates of GAS to laminin was significantly higher than the adherence displayed by isolates of low invasiveness. Antibiotic treatment caused significant reductions in adherence to laminin in all three groups of strains. Penicillin was more successful in reducing the adherence abilities of the tested GAS strains than erythromycin.

Indexed as

Anti-Bacterial AgentsBacterial AdhesionErythromycinHumansLamininMicrobial Sensitivity TestsPenicillinsStreptococcus pyogenesAnti-Bacterial AgentsErythromycinLamininPenicillins

Identifiers

PMID26270594
PMCPMC4569834

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.