Evidence map›Paper›PMID 26270579›Full record

ArticlePediatric research2015

Augmented cardiovascular responses to episodes of repetitive compared with isolated respiratory events in preschool children with sleep-disordered breathing.

Lisa M Walter, Sarah N Biggs, Lauren C Nisbet, Aidan J Weichard, Milou Muntinga, Margot J Davey, Vicki Anderson, Gillian M Nixon, Rosemary S C Horne

Open access · bronzeAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Pediatric research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Lisa M WalterThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
Sarah N BiggsThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
Lauren C NisbetThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
Aidan J WeichardThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
Milou MuntingaThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
Margot J DaveyThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
Vicki AndersonClinical Sciences Research, Murdoch Children's Research Institute, Melbourne, Australia.
Gillian M NixonThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
Rosemary S C HorneThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
Hudson Institute of Medical Research · AUMonash University · AUMurdoch Children's Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildhood sleep disordered breathing (SDB) presents as isolated respiratory events or episodes of consecutive repetitive events. We hypothesized that the surge in blood pressure (BP) and heart rate (HR) would be greater at the termination of events during episodes of repetitive events than following isolated events.

methods% change in HR and pulse transit time (PTT; inverse surrogate of BP) were calculated from the last half of an event to: (i) between successive repetitive events; (ii) termination of the last repetitive event; (iii) event termination for isolated events.

results69% of the children exhibiting both isolated and repetitive events had more repetitive than isolated events. %HR change between repetitive events (27 ± 1%) was greater than at event termination for isolated events (17 ± 1%; P < 0.001). %PTT change at the termination of the last repetitive event (-8 ± 2%) was greater than at the termination of isolated events (-2 ± 2%; P < 0.05).

conclusionEpisodes of repetitive respiratory events evoke a greater acute cardiovascular response, including surges in BP and HR between events, than do isolated events. Given that the majority of respiratory events in preschool children occur as repetitive episodes, this finding should be taken into account when assessing the impact of respiratory events for a given child.

Indexed as

Blood PressureHeart RateAge FactorsCardiovascular SystemChild, PreschoolFemaleHumansLungMalePrognosisSleep Apnea SyndromesTime Factors

Identifiers

PMID26270579
OpenAlexW1466298266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.