Trial reportPediatric research2015
Low-glycemic index diet may improve insulin sensitivity in obese children.
Trial report in Pediatric research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 5 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Effects of carbohydrate-modified diets on insulin sensitivity in children and adolescents with overweight/obesity: a systematic review and meta-analysis of randomized controlled trials.BMC endocrine disorders · 2026Pooled it
- Low-Glycemic Index Diets as an Intervention in Metabolic Diseases: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- Impact of Lifestyle Intervention Programs for Children and Adolescents with Overweight or Obesity on Body Weight and Selected Cardiometabolic Factors-A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- What change in body mass index is associated with improvement in percentage body fat in childhood obesity? A meta-regression.BMJ open · 2019Pooled it
- Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents aged 12 to 17 years.The Cochrane database of systematic reviews · 2017Pooled it
- Trial
- Effects of low-glycemic index diet on plasma adipokines in obese children.Pediatric research · 2021Trial
- Single Autoantibody Positivity in Pediatric Type 1 Diabetes: Serological Profiles, Clinical Trajectories and Implications for Early Disease Monitoring-A Case Series of Seven Patients.Life (Basel, Switzerland) · 2026Article
- Dietary bioactive compounds targeting insulin resistance: mechanisms and preventive potential.Frontiers in nutrition · 2026Review
- Bioelectrical Impedance Analysis Versus Dual X-Ray Absorptiometry for Obesity Assessment in Pediatric Populations: A Systematic Review.Diagnostics (Basel, Switzerland) · 2025Review
- Review
- Obesity and malnutrition in children and adults: A clinical review.Obesity pillars · 2023Review
- Glycemic and Satiety Response to Three Mexican Honey Varieties.Foods (Basel, Switzerland) · 2023Article
- The Effectiveness of a Low Glycemic Index/Load Diet on Cardiometabolic, Glucometabolic, and Anthropometric Indices in Children with Overweight or Obesity: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2023Review
- Article
- Association between dietary glycemic index and non-alcoholic fatty liver disease in patients with type 2 diabetes mellitus.Frontiers in endocrinology · 2023Article
- Dietary protein and the glycemic index handle insulin resistance within a nutritional program for avoiding weight regain after energy-restricted induced weight loss.Nutrition & metabolism · 2022Article
- Article
- Familial dietary intervention in children with excess body weight and its impact on eating habits, anthropometric and biochemical parameters.Frontiers in endocrinology · 2022Article
- Science for Kids: Effects of low-glycemic index diet on plasma adipokines in childhood obesity.Pediatric research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA low-glycemic index (GI) diet may be beneficial for weight management due to its effect on insulin metabolism and satiety.
methodsObese children aged 9-16 y were randomly assigned either a low-GI diet or a low-fat diet (control group) for 6 mo. Body composition changes were measured by dual-energy X-ray absorptiometry and bioelectrical impedance analysis. Insulin sensitivity was measured by fasting plasma glucose and insulin.
resultsFifty-two participants completed the study (mean age: 12.0 ± 2.0 y, 35 boys); both groups showed significantly decreased BMI z-score but similar changes in fat and fat-free mass. The low-GI group demonstrated a significant decline in fasting plasma insulin (22.2 ± 14.3 to 13.7 ± 10.9 mU/l; P = 0.004) and homeostatic model of assessment-insulin resistance (4.8 ± 3.3 to 2.9 ± 2.3; P = 0.007), whereas the control group did not. However, general linear model showed no significant difference in insulin resistance between groups after adjusting for baseline levels, suggesting that the greater reduction in insulin resistance in the low-GI group may be explained by higher baseline values.
conclusionDespite subtle effects on body composition, a low-GI diet may improve insulin sensitivity in obese children with high baseline insulin. A bigger study in obese children with insulin resistance could be worthwhile to confirm our findings.
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