Evidence map›Paper›PMID 26270005›Full record

ArticleChest2015

The Association Between Indwelling Arterial Catheters and Mortality in Hemodynamically Stable Patients With Respiratory Failure: A Propensity Score Analysis.

Douglas J Hsu, Mengling Feng, Rishi Kothari, Hufeng Zhou, Kenneth P Chen, Leo A Celi

Open access · bronzeAbstract read
In one paragraph

Article in Chest, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Invasive and non-invasive monitoring in the ICU.Trauma surgery & acute care open · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Observational
  11. Getting What You Pay For.Annals of the American Thoracic Society · 2022
    Article
  12. Article
  13. Article
  14. Early veBMJ open · 2021
    Article
  15. Red Blood Cell Distribution Width Is Associated with All-Cause Mortality in Critically Ill Patients with Cardiogenic Shock.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  16. Article
  17. Article
  18. The MIMIC Code Repository: enabling reproducibility in critical care research.Journal of the American Medical Informatics Association : JAMIA · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Douglas J HsuDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, MA. Electronic address: dhsu@bidmc.harvard.edu.
Mengling FengLaboratory of Computational Physiology, Massachusetts Institute of Technology, Cambridge, MA; Institute for Infocomm Research, Singapore.
Rishi KothariDepartment of Anesthesia, Mount Sinai Hospital, New York, NY.
Hufeng ZhouDepartment of Medicine, Brigham and Women's Hospital, Boston, MA; Department of Microbiology and Immunobiology, Harvard University, Cambridge, MA.
Kenneth P ChenDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, MA.
Leo A CeliDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, MA; Laboratory of Computational Physiology, Massachusetts Institute of Technology, Cambridge, MA.
Beth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USMassachusetts Institute of Technology · USMount Sinai Hospital · US

Funding

Integrating Data, Models, and Reasoning in Critical CareR01EB001659 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI MARK, ROGER GREENWOOD · 2003 to 2012
$9.8M
Research Resource for Complex Physiologic SignalsR01GM104987 · NIGMS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI GOLDBERGER, ARY LOUIS, MARK, ROGER GREENWOOD · 2012 to 2019
$5.8M
NIBIB NIH HHS R01 EB001659NIGMS NIH HHS R01 GM104987
6 · The paper itself

Abstract

backgroundIndwelling arterial catheters (IACs) are used extensively in the ICU for hemodynamic monitoring and for blood gas analysis. IAC use also poses potentially serious risks, including bloodstream infections and vascular complications. The purpose of this study was to assess whether IAC use was associated with mortality in patients who are mechanically ventilated and do not require vasopressor support.

methodsThis study used the Multiparameter Intelligent Monitoring in Intensive Care II database, consisting of > 24,000 patients admitted to the Beth Israel Deaconess Medical Center ICU between 2001 and 2008. Patients requiring mechanical ventilation who did not require vasopressors or have a diagnosis of sepsis were identified, and the primary outcome was 28-day mortality. A model based on patient demographics, comorbidities, vital signs, and laboratory results was developed to estimate the propensity for IAC placement. Patients were then propensity matched, and McNemar test was used to evaluate the association of IAC with 28-day mortality.

resultsWe identified 1,776 patients who were mechanically ventilated who met inclusion criteria. There were no differences in the covariates included in the final propensity model between the IAC and non-IAC propensity-matched groups. For the matched cohort, there was no difference in 28-day mortality between the IAC group and the non-IAC group (14.7% vs 15.2%; OR, 0.96; 95% CI, 0.62-1.47).

conclusionsIn hemodynamically stable patients who are mechanically ventilated, the presence of an IAC is not associated with a difference in 28-day mortality. Validation in other datasets, as well as further analyses in other subgroups, is warranted.

Indexed as

Catheterization, PeripheralRespiratory InsufficiencyAdultAgedBlood Gas AnalysisCatheters, IndwellingFemaleHemodynamicsHospital MortalityHumansIntensive Care UnitsLength of StayMaleMiddle AgedMonitoring, PhysiologicOutcome Assessment, Health Care

Identifiers

PMID26270005
PMCPMC4665738
OpenAlexW2181664764

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.