ReviewCurrent epidemiology reports
Current Applications of Genetic Risk Scores to Cardiovascular Outcomes and Subclinical Phenotypes.
Review in Current epidemiology reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed.
- Genetic risk score for risk prediction of diabetic nephropathy in Han Chinese type 2 diabetes patients.Scientific reports · 2019Trial
- Validation of a genetic risk score for atrial fibrillation: A prospective multicenter cohort study.PLoS medicine · 2018Trial
- Genetic impact of central adiposity on systolic blood pressure in females: interaction and mediation by TG/HDL-C, HbA1c, and uric acid across BMI categories.International journal of obesity (2005) · 2025Article
- TLR2 c.374C>T variant linked to natural resistance against brucellosis in Italian Mediterranean river buffalo.BMC veterinary research · 2025Article
- Epigenomic partitioning of a polygenic risk score for asthma reveals distinct genetically driven disease pathways.The European respiratory journal · 2024Article
- Influence of blood pressure polygenic risk scores and environmental factors on coronary artery disease in the Korean Genome and Epidemiology Study.Journal of human hypertension · 2024Article
- Advancing stroke genetics in Hawai'i and the Pacific Islands.Frontiers in stroke · 2023Article
- Early-life farm exposures and eczema among adults in the Agricultural Lung Health Study.The journal of allergy and clinical immunology. Global · 2022Article
- Review
- The Translation and Commercialisation of Biomarkers for Cardiovascular Disease-A Review.Frontiers in cardiovascular medicine · 2022Review
- Genetic factors increase the identification efficiency of predictive models for dyslipidaemia: a prospective cohort study.Lipids in health and disease · 2021Article
- Genetic information improves the prediction of major adverse cardiovascular events in the GENEMACOR population.Genetics and molecular biology · 2021Article
- Apolipoprotein C-III and cardiovascular diseases: when genetics meet molecular pathologies.Molecular biology reports · 2021Review
- Solar Ultraviolet Radiation and Vitamin D Deficiency on Epstein-Barr Virus Reactivation: Observational and Genetic Evidence From a Nasopharyngeal Carcinoma-Endemic Population.Open forum infectious diseases · 2020Article
- Genetically Elevated LDL Associates with Lower Risk of Intracerebral Hemorrhage.Annals of neurology · 2020Article
- Genetic risk prediction of the plasma triglyceride response to independent supplementations with eicosapentaenoic and docosahexaenoic acids: the ComparED Study.Genes & nutrition · 2020Article
- Statistical learning approaches in the genetic epidemiology of complex diseases.Human genetics · 2020Review
- Polygenic approaches to detect gene-environment interactions when external information is unavailable.Briefings in bioinformatics · 2019Review
- Genetic Basis of Obesity and Type 2 Diabetes in Africans: Impact on Precision Medicine.Current diabetes reports · 2019Review
- The Gene Score for Predicting Hypertriglyceridemia: New Insights from a Czech Case-Control Study.Molecular diagnosis & therapy · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Genetic risk scores are a useful tool for examining the cumulative predictive ability of genetic variation on cardiovascular disease. Important considerations for creating genetic risk scores include the choice of genetic variants, weighting, and comparability across ethnicities. Genetic risk scores that use information from genome-wide meta-analyses can successfully predict cardiovascular outcomes and subclinical phenotypes, yet there is limited clinical utility of these scores beyond traditional cardiovascular risk factors in many populations. Novel uses of genetic risk scores include evaluating the genetic contribution of specific intermediate traits or risk factors to cardiovascular disease, risk prediction in high-risk populations, gene-by-environment interaction studies, and Mendelian randomization studies. Though questions remain about the ultimate clinical utility of the genetic risk score, further investigation in high-risk populations and new ways to combine genetic risk scores with traditional risk factors may prove to be fruitful.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.