ArticleAmerican journal of cancer research2015
Different patterns in the prognostic value of age for bladder cancer-specific survival depending on tumor stages.
Article in American journal of cancer research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Fear of Cancer Recurrence and Its Associated Factors in Bladder Cancer Patients of Different Age Stages: A Cross-Sectional Study.Cancer management and research · 2025Article
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- Surveillance of prognostic risk factors in patients with SCCB using artificial intelligence: a retrospective study.Scientific reports · 2023Article
- Preoperative Fibrinogen-to-Albumin Ratio as Potential Predictor of Bladder Cancer: A Monocentric Retrospective Study.Medicina (Kaunas, Lithuania) · 2022Article
- Bladder cancer, inflammageing and microbiomes.Nature reviews. Urology · 2022Review
- Prognostic Factors for Bladder Cancer Patients in Malaysia: A Population-Based Study.International journal of environmental research and public health · 2022Article
- Characterization of PHGDH expression in bladder cancer: potential targeting therapy with gemcitabine/cisplatin and the contribution of promoter DNA hypomethylation.Molecular oncology · 2020Article
- Do Younger Patients with Muscle-Invasive Bladder Cancer have Better Outcomes?Journal of clinical medicine · 2019Article
- Enhancing E-cadherin expression via promoter-targeted miR-373 suppresses bladder cancer cells growth and metastasis.Oncotarget · 2017Article
- Age at diagnosis, obesity, smoking, and molecular subtypes in muscle-invasive bladder cancer.Cancer causes & control : CCC · 2017Article
- Dual tumor-suppressors miR-139-5p and miR-139-3p targeting matrix metalloprotease 11 in bladder cancer.Cancer science · 2016Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To compare the pathological features and long-term survival of bladder cancer (BCa) in young patients with elderly counterparts. Using the U.S. National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) population-based data, we identified 93115 patients with non-metastatic bladder cancer diagnosed between 1988 and 2003. Patients were categorized into young (50 years and under) and elderly groups (over 50 years of age). The overall and five-year bladder cancer specific survival (BCSS) data were obtained using Kaplan-Meier plots. Multivariable Cox regression models were built for the analysis of long-term survival outcomes and risk factors. There were significant differences between the two groups in primary site, pathologic grading, histologic type, AJCC stage (p<0.001). The overall and 5-year cancer specific survival rates were 88.1% and 90.8% in young group, 64.8% and 81.3% in elderly group, which had significant difference in both univariate and multivariate analysis (p<0.001). Further analysis showed this significant difference existed across all the AJCC stage patients. The study findings show different patterns in the prognostic value of age for determining BCSS, depending on the tumor stages. Compared with elderly patients, young patients with bladder cancer surgery appear to have unique characteristics and a higher overall and cancer specific survival rate.
Indexed as
Identifiers
26269768PMC4529628W1428915377What OpenQuestion holds
Registered trials
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