ReviewWorld journal of emergency surgery : WJES2015
The role of the open abdomen procedure in managing severe abdominal sepsis: WSES position paper.
Review in World journal of emergency surgery : WJES, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03163095 (Closed Versus Open Abdomen in the Surgical Treatment of Severe Secondary Peritonitis), which is not on this map. Cited by 71 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Closed Versus Open Abdomen in the Surgical Treatment of Severe Secondary Peritonitis: a Randomized Controlled Clinical Trial
Who cites it
71 citing papers in PubMed, 2 syntheses or guidelines pooled it, 180 citations in OpenAlex.
- Negative pressure wound therapy for managing the open abdomen in non-trauma patients.The Cochrane database of systematic reviews · 2022Pooled it
- The role of damage control surgery in the treatment of perforated colonic diverticulitis: a systematic review and meta-analysis.International journal of colorectal disease · 2021Pooled it
- The unrestricted global effort to complete the COOL trial.World journal of emergency surgery : WJES · 2023Trial
- Resuscitative endovascular balloon occlusion of the aorta (REBOA) as a potential facilitator of definitive fascial closure in the open abdomen: a retrospective study in massive traumatic hemorrhage.Journal of trauma and injury · 2026Article
- Article
- Mesh-mediated fascial traction for open abdomen management to prevent planned ventral hernias: a retrospective cohort.Langenbeck's archives of surgery · 2025Article
- Visceral Arterial Pseudoaneurysms-A Clinical Review.Medicina (Kaunas, Lithuania) · 2025Review
- The effect of damage control laparotomy on surgical-site infection risks after emergent intestinal surgery.Surgery · 2024Article
- Entero-Cutaneous and Entero-Atmospheric Fistulas: Insights into Management Using Negative Pressure Wound Therapy.Journal of clinical medicine · 2024Review
- Bilateral rectus muscle turning-over for complicated and eventrated abdominal wall hernias: results of a novel method.Acta cirurgica brasileira · 2024Article
- Open or closed abdomen post laparotomy to control severe abdominal sepsis: a survival analysis.Revista do Colegio Brasileiro de Cirurgioes · 2024Article
- Article
- The open abdomen in trauma, acute care, and vascular and endovascular surgery: comprehensive, expert, narrative review.BJS open · 2023Review
- Patients with an Open Abdomen in Asian, American and European Continents: A Comparative Analysis from the International Register of Open Abdomen (IROA).World journal of surgery · 2023Article
- Abdominal Compartment Syndrome in Acute Pancreatitis: A Narrative Review.Diagnostics (Basel, Switzerland) · 2022Review
- Retrospective Study of Indications and Outcomes of Open Abdomen with Negative Pressure Wound Therapy Technique for Abdominal Sepsis in a Tertiary Referral Centre.Antibiotics (Basel, Switzerland) · 2022Article
- Study of damage control strategy for non-traumatic diseases: a single-center observational study.European journal of medical research · 2022Observational
- Vacuum-assisted closure versus on-demand relaparotomy in patients with secondary peritonitis-the VACOR trial: protocol for a randomised controlled trial.World journal of emergency surgery : WJES · 2022Article
- Factors influencing the fascial closure rate after open abdomen treatment: Results from the European Hernia Society (EuraHS) Registry : Surgical technique matters.Hernia : the journal of hernias and abdominal wall surgery · 2022Article
- Two surgeons' collaboration to close an extreme open abdomen with loss of domain utilizing the abdominal dynamic tissue system and porcine urinary bladder matrix.Proceedings (Baylor University. Medical Center) · 2022Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
38 authors at 20 institutions in 21 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The open abdomen (OA) procedure is a significant surgical advance, as part of damage control techniques in severe abdominal trauma. Its application can be adapted to the advantage of patients with severe abdominal sepsis, however its precise role in these patients is still not clear. In severe abdominal sepsis the OA may allow early identification and draining of any residual infection, control any persistent source of infection, and remove more effectively infected or cytokine-loaded peritoneal fluid, preventing abdominal compartment syndrome and deferring definitive intervention and anastomosis until the patient is appropriately resuscitated and hemodynamically stable and thus better able to heal. However, the OA may require multiple returns to the operating room and may be associated with significant complications, including enteroatmospheric fistulas, loss of abdominal wall domain and large hernias. Surgeons should be aware of the pathophysiology of severe intra-abdominal sepsis and always keep in mind the option of using open abdomen to be able to use it in the right patient at the right time.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.