ArticleWorld journal of gastroenterology2015
Helicobacter pylori infection is associated with gallstones: Epidemiological survey in China.
Article in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Bile microbiota in gallbladder stones and its association withFrontiers in microbiology · 2025Pooled it
- Pooled it
- The Relationship betweenCanadian journal of gastroenterology & hepatology · 2021Pooled it
- Significant Association Between Gallstone Disease and Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2016Pooled it
- Minilap-assisted modified single-incisionPeerJ · 2026Article
- Research progress on the role of microbiota in the pathogenesis of gallstone disease.Frontiers in microbiology · 2025Review
- Helicobacter Pylori Infection as an Independent Risk Factor for Kidney Stone Formation in China: A Cross-Sectional Study.Infection and drug resistance · 2025Article
- Analysis between Helicobacter pylori infection and hepatobiliary diseases.Frontiers in cellular and infection microbiology · 2025Article
- Article
- Lipopolysaccharide in Bile Promotes the Neutrophil Extracellular Traps-Induced Gallstone Formation by Activating the Gallbladder Immune Barrier.ImmunoTargets and therapy · 2024Article
- The link betweenAnnals of hepato-biliary-pancreatic surgery · 2023Review
- A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.Cellular and molecular gastroenterology and hepatology · 2021Article
- Gallstone Disease and Microbiome.Microorganisms · 2020Review
- Linking Helicobacter pylori with gallbladder and biliary tract cancer in Moroccan population using clinical and pathological profiles.Bioinformation · 2019Article
- Frequency of gallstones and mean BMI in decompensated cirrhosis.The Pan African medical journal · 2018Article
- Cholecystectomy and duodenogastric reflux: interacting effects over the gastric mucosa.SpringerPlus · 2016Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo elucidate the prevalence and risk factors for gallstones, primarily focusing on Helicobacter pylori (H. pylori) infection.
methodsA total of 10016 Chinese subjects, who had undergone physical examination, fasting (13)C urea breath test and abdominal ultrasonography, had sufficient blood test data, and had finished a questionnaire, were included in this cross-sectional study. Participants (n = 1122) who had previous eradication of H. pylori were studied separately.
resultsGallstones were discovered in 9.10% of men and 8.58% of women, with no significant sex difference. Multivariate analyses displayed that age, aspartate aminotransferase, total cholesterol, H. pylori infection, hepatitis C virus (HCV) infection, and fatty liver had a significant association with gallstones (P < 0.05). Successive multiple logistic regression analysis including index of odds ratio (OR) and standardized coefficient (β) indicated that older age (OR/β = 1.056/0.055), H. pylori infection (OR/β = 1.454/0.109), HCV infection (OR/β = 1.871/0.123), and fatty liver (OR/β = 1.947/0.189) had a significant positive association with gallstones. After age stratification, H. pylori infection and fatty liver still had a significant positive association with gallstones in any age-specific groups, whereas HCV infection had a significant positive association in patients aged > 40 years. The prevalence of gallstones among H. pylori-positive, H. pylori-eradicated, and H. pylori-negative subjects was 9.47%, 9.02%, and 8.46%, respectively. The matched analysis showed that gallstones among H. pylori eradicated subjects was significantly lower compared with H. pylori-positive subjects (P < 0.05).
conclusionH. pylori infection and fatty liver have a significant positive association with gallstones. H. pylori eradication may lead to prevention of gallstones.
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