Next-generation sequencing-based genome diagnostics across clinical genetics centers: implementation choices and their effects.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed.

1. Transforming NICU care: rapid WES and transcriptomics-validation, social impact, and cost analysis.European journal of pediatrics · 2025
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2. Indigenous population genome databases for India and South Asia: emerging need for health and social applications.Journal of genetics · 2023
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3. A capillary electrophoresis-based multiplex PCR assay for expanded carrier screening in the eastern Han Chinese population.NPJ genomic medicine · 2022
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4. Implementation of Early Next-Generation Sequencing for Inborn Errors of Immunity: A Prospective Observational Cohort Study of Diagnostic Yield and Clinical Implications in Dutch Genome Diagnostic Centers.Frontiers in immunology · 2021
   Observational
5. Evaluation of copy number variant detection from panel-based next-generation sequencing data.Molecular genetics & genomic medicine · 2019
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6. Comparative genomics of Tunisian Leishmania major isolates causing human cutaneous leishmaniasis with contrasting clinical severity.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2017
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7. Reassessment of Genomic Sequence Variation to Harmonize Interpretation for Personalized Medicine.American journal of human genetics · 2016
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8. Recommendations for the integration of genomics into clinical practice.Genetics in medicine : official journal of the American College of Medical Genetics · 2016
   Review
9. Evaluating the necessity of PCR duplicate removal from next-generation sequencing data and a comparison of approaches.BMC bioinformatics · 2016
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10. Clinical Diagnosis of Mendelian Disorders Using a Comprehensive Gene-Targeted Panel Test for Next-Generation Sequencing.Yonago acta medica · 2016
    Article
11. Scenario drafting for early technology assessment of next generation sequencing in clinical oncology.BMC cancer · 2016
    Article
12. Monogenic causes of stroke: now and the future.Journal of neurology · 2015
    Review
13. Experiences with obtaining informed consent for genomic sequencing.American journal of medical genetics. Part A · 2015
    Article
14. Genomic analysis in the clinic: benefits and challenges for health care professionals and patients in Brazil.Journal of community genetics · 2015
    Article
15. Heart failure: advanced development in genetics and epigenetics.BioMed research international · 2015
    Review

Corrections and comments

• Erratum for
  Next-generation sequencing-based genome diagnostics across clinical genetics centers: implementation choices and their effects.2015 · Mook, Olaf R [added]

Authors and funding

48 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.