Evidence map›Paper›PMID 26269030›Full record

SynthesisActa neurochirurgica2015

Epidemiology of traumatic brain injury in Europe.

Wouter Peeters, Ruben van den Brande, Suzanne Polinder, Alexandra Brazinova, Ewout W Steyerberg, Hester F Lingsma, Andrew I R Maas

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Acta neurochirurgica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06171568 (Study of the One-year Outcomes of Patients Hospitalized in the Lariboisière Neurosurgery Department), which is not on this map. Cited by 305 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
305citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06171568 unknown statusnot on this mapstarted 2024, after this paper: background citation

Study of the One-year Outcomes of Patients Hospitalized in the Lariboisière Neurosurgery Department

TypeobservationalSponsorAssistance Publique - Hôpitaux de ParisRan2024 to 2025Enrolled400ConditionsBrain InjuriesArmsTests and questionnaires
3 · Its place in the literature

Who cites it

305 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Severe traumatic brain injury and long-term survival: a meta-analysis on life expectancy and mortality trends.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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245 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wouter PeetersUniversity of Antwerp, Antwerp, Belgium.
Ruben van den BrandeUniversity of Antwerp, Antwerp, Belgium.
Suzanne PolinderDepartment of Public Health, Centre for Medical Decision Making, Erasmus MC, Rotterdam, The Netherlands.
Alexandra BrazinovaFaculty of Health Sciences and Social Work, Trnava University, Trnava, Slovak Republic.
Ewout W SteyerbergDepartment of Public Health, Centre for Medical Decision Making, Erasmus MC, Rotterdam, The Netherlands.
Hester F LingsmaDepartment of Public Health, Centre for Medical Decision Making, Erasmus MC, Rotterdam, The Netherlands.
Andrew I R MaasUniversity of Antwerp, Antwerp, Belgium. andrew.maas@uza.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraumatic brain injury (TBI) is a critical public health and socio-economic problem throughout the world, making epidemiological monitoring of incidence, prevalence and outcome of TBI necessary. We aimed to describe the epidemiology of traumatic brain injury in Europe and to evaluate the methodology of incidence studies.

methodWe performed a systematic review and meta-analyses of articles describing the epidemiology of TBI in European countries. A search was conducted in the PubMed electronic database using the terms: epidemiology, incidence, brain injur*, head injur* and Europe. Only articles published in English and reporting on data collected in Europe between 1990 and 2014 were included.

resultsIn total, 28 epidemiological studies on TBI from 16 European countries were identified in the literature. A great variation was found in case definitions and case ascertainment between studies. Falls and road traffic accidents (RTA) were the two most frequent causes of TBI, with falls being reported more frequently than RTA. In most of the studies a peak TBI incidence was seen in the oldest age groups. In the meta-analysis, an overall incidence rate of 262 per 100,000 for admitted TBI was derived.

conclusionsInterpretation of published epidemiologic studies is confounded by differences in inclusion criteria and case ascertainment. Nevertheless, changes in epidemiological patterns are found: falls are now the most common cause of TBI, most notably in elderly patients. Improvement of the quality of standardised data collection for TBI is mandatory for reliable monitoring of epidemiological trends and to inform appropriate targeting of prevention campaigns.

Indexed as

Accidental FallsAccidents, TrafficAdultAgedBrain InjuriesEuropeFemaleHospitalizationHumansMaleMiddle AgedEpidemiologyExternal causeIncidenceMortalitySystematic reviewTraumatic brain injury

Identifiers

PMID26269030
PMCPMC4569652

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.