ArticleBMC genomics2015
Diversity of the cell-wall associated genomic island of the archaeon Haloquadratum walsbyi.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Large diversity in the O-chain biosynthetic cluster within populations of Pelagibacterales.mBio · 2025Article
- Novel viruses of Haloquadratum walsbyi expand the known archaeal virosphere of hypersaline environments.The ISME journal · 2025Article
- Global dominance of Haloquadratum walsbyi by a single genomovar with distinct gene content and viral cohorts from close relatives.The ISME journal · 2025Article
- Article
- Differences in gene expression patterns between cultured and naturalFrontiers in microbiology · 2022Article
- Review
- Archaeal cell surface biogenesis.FEMS microbiology reviews · 2018Article
- Genome Variation in the Model Halophilic BacteriumFrontiers in microbiology · 2018Article
- Transcriptome analysis of Haloquadratum walsbyi: vanity is but the surface.BMC genomics · 2017Article
- New insights into marine group III Euryarchaeota, from dark to light.The ISME journal · 2017Article
- Metagenomic Insights into the Uncultured Diversity and Physiology of Microbes in Four Hypersaline Soda Lake Brines.Frontiers in microbiology · 2016Article
- An Integrative Genomic Island Affects the Adaptations of the Piezophilic Hyperthermophilic ArchaeonFrontiers in microbiology · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHaloquadratum walsbyi represents up to 80% of cells in NaCl-saturated brines worldwide, but is notoriously difficult to maintain under laboratory conditions. In order to establish the extent of genetic diversity in a natural population of this microbe, we screened a H. walsbyi enriched metagenomic fosmid library and recovered seven novel version of its cell-wall associated genomic island. The fosmid inserts were sequenced and analysed.
resultsThe novel cell-wall associated islands delineated two major clades within H. walsbyi. The islands predominantly contained genes putatively involved in biosynthesis of surface layer, genes encoding cell surface glycoproteins and genes involved in envelope formation. We further found that these genes are maintained in the population and that the diversity of this region arises through homologous recombination but also through the action of mobile genetic elements, including viruses.
conclusionsThe population of H. walsbyi in the studied saltern brine is composed of numerous clonal lineages that differ in surface structures including the cell wall. This type of variation probably reflects a number of mechanisms that minimize the infection rate of predating viruses.
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