Evidence map›Paper›PMID 26268947›Full record

ArticleBMC urology2015

Erectile function in men with end-stage liver disease improves after living donor liver transplantation.

You-Chiuan Chien, Heng-Chieh Chiang, Ping-Yi Lin, Yao-Li Chen

Open access · goldAbstract read
In one paragraph

Article in BMC urology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Review
  10. Sexual dysfunction and male infertility.Nature reviews. Urology · 2018
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

You-Chiuan ChienDivision of urology, Department of Surgery, Changhua Christian Hospital, No.135, Nansiao St. Changhua city, Changhua county, 50006, Taiwan. cch156967@gmail.com.
Heng-Chieh ChiangDivision of urology, Department of Surgery, Changhua Christian Hospital, No.135, Nansiao St. Changhua city, Changhua county, 50006, Taiwan. 49264@cch.org.tw.
Ping-Yi LinTransplant Medicine & Surgery Research Centre, Changhua Christian Hospital, Changhua, Taiwan. 69221@cch.org.tw.
Yao-Li ChenSchool of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. 31560@cch.org.tw.
Changhua Christian Hospital · TWKaohsiung Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImpaired liver function in men can result in erectile dysfunction or hypogonadism or both. We investigated whether living donor liver transplantation (LDLT) results in improvement in male sexual function.

methodsA total of 58 patients with end-stage liver disease (ESLD) were included in this prospective, cross-sectional study. Erectile function was measured before and after LDLT using a five-item modified version of the International Index of Erectile Function scale (IIEF-5) and hypogonadism was evaluated before and after LDLT using the Androgen Deficiency in the Aging Male (ADAM) questionnaire. Differences in mean values from the questionnaires before and after the operation were than evaluated to determine whether there is an association between LDLT and improvement in sexual function.

resultsWe found that mean IIEF-5 scores significantly increased after LDLT (from 11.7 ± 7.7 before LDLT to 14.7 ± 7.5 after LDLT, p < 0.01), indicating that the operation played a role in improving erectile function. In addition, the prevalence of hypogonadism among the patients with ESLD decreased markedly after liver transplantation (hypogonadism before LDLT, n = 41 versus hypogonadism after LDLT, n = 31, p = 0.03). Patients with hypogonadism reported a higher prevalence of erectile dysfunction after LDLT than patients without hypogonadism (p < 0.01).

conclusionsLDLT results in improvement in erectile function. In addition, improvement in erectile function is associated with self-reported absence of hypogonadism.

Indexed as

Liver TransplantationLiving DonorsPatient SatisfactionDiagnostic Self EvaluationEnd Stage Liver DiseaseErectile DysfunctionHumansHypogonadismMaleMiddle AgedTreatment Outcome

Identifiers

PMID26268947
PMCPMC4535392
OpenAlexW1822240380

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.